Carbohydrate-based macromolecular biomaterials
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
M Thépaut, J Luczkowiak, C Vivès, N Labiod… - PLoS …, 2021 - journals.plos.org
The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history.
Despite early identification of ACE2 as the receptor for viral spike protein, much remains to …
Despite early identification of ACE2 as the receptor for viral spike protein, much remains to …
[HTML][HTML] Recent advances in antiviral drug development towards dengue virus
B Troost, JM Smit - Current opinion in virology, 2020 - Elsevier
Highlights•Evaluating drug efficacy, specificity and toxicity may help to develop an optimal
treatment regime for in vivo studies.•Measuring time to resolve viremia in vivo may help to …
treatment regime for in vivo studies.•Measuring time to resolve viremia in vivo may help to …
Exploring multivalent carbohydrate–protein interactions by NMR
JI Quintana, U Atxabal, L Unione, A Ardá… - Chemical Society …, 2023 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) has been widely employed to assess diverse features
of glycan–protein molecular recognition events. Different types of qualitative and quantitative …
of glycan–protein molecular recognition events. Different types of qualitative and quantitative …
Multivalent glycosystems for human lectins
M Martínez-Bailén, J Rojo… - Chemical Society …, 2023 - pubs.rsc.org
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …
pathological, which have attracted the interest of the scientific community working in the …
Lipid-based mRNA vaccine delivery systems
P Midoux, C Pichon - Expert review of vaccines, 2015 - Taylor & Francis
Synthetic mRNAs can become biopharmaceutics allowing vaccination against cancer,
bacterial and virus infections. Clinical trials with direct administration of synthetic mRNAs …
bacterial and virus infections. Clinical trials with direct administration of synthetic mRNAs …
Synthesis of highly efficient multivalent disaccharide/[60] fullerene nanoballs for emergent viruses
J Ramos-Soriano, JJ Reina, BM Illescas… - Journal of the …, 2019 - ACS Publications
After the last epidemic of the Zika virus (ZIKV) in Brazil that peaked in 2016, growing
evidence has been demonstrated of the link between this teratogenic flavivirus and …
evidence has been demonstrated of the link between this teratogenic flavivirus and …
Strategies to overcome HIV drug resistance-current and future perspectives
A Temereanca, S Ruta - Frontiers in Microbiology, 2023 - frontiersin.org
The availability of combined antiretroviral therapy (cART) has revolutionized the course of
HIV infection, suppressing HIV viremia, restoring the immune system, and improving the …
HIV infection, suppressing HIV viremia, restoring the immune system, and improving the …
Glycan-based cell targeting to modulate immune responses
T Johannssen, B Lepenies - Trends in Biotechnology, 2017 - cell.com
Glycosylation is an integral post-translational modification present in more than half of all
eukaryotic proteins. It affects key protein functions, including folding, stability, and …
eukaryotic proteins. It affects key protein functions, including folding, stability, and …