[HTML][HTML] Tuberculosis and lung damage: from epidemiology to pathophysiology
S Ravimohan, H Kornfeld, D Weissman… - European respiratory …, 2018 - Eur Respiratory Soc
A past history of pulmonary tuberculosis (TB) is a risk factor for long-term respiratory
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …
impairment. Post-TB lung dysfunction often goes unrecognised, despite its relatively high …
Innate immunity in tuberculosis: host defense vs pathogen evasion
CH Liu, H Liu, B Ge - Cellular & molecular immunology, 2017 - nature.com
The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …
Immunology of Mycobacterium tuberculosis Infections
JK Sia, J Rengarajan - Microbiology spectrum, 2019 - Am Soc Microbiol
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
[HTML][HTML] Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
L Moreira-Teixeira, PJ Stimpson, E Stavropoulos… - Nature …, 2020 - nature.com
Tuberculosis (TB) is a leading cause of mortality due to infectious disease, but the factors
determining disease progression are unclear. Transcriptional signatures associated with …
determining disease progression are unclear. Transcriptional signatures associated with …
[HTML][HTML] Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm
Aortic aneurysm is an asymptomatic disease with dire outcomes if undiagnosed. Aortic
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …
Pathogenicity and virulence of Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …
[HTML][HTML] Neutrophil extracellular traps in pulmonary diseases: too much of a good thing?
Neutrophil extracellular traps (NETs) arise from the release of granular and nuclear contents
of neutrophils in the extracellular space in response to different classes of microorganisms …
of neutrophils in the extracellular space in response to different classes of microorganisms …
[HTML][HTML] Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine
SG Hansen, DE Zak, G Xu, JC Ford, EE Marshall… - Nature medicine, 2018 - nature.com
Despite widespread use of the bacille Calmette–Guérin (BCG) vaccine, tuberculosis (TB)
remains a leading cause of global mortality from a single infectious agent (Mycobacterium …
remains a leading cause of global mortality from a single infectious agent (Mycobacterium …
[HTML][HTML] Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies
D Tiwari, AR Martineau - Seminars in Immunology, 2023 - Elsevier
Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …
Cavitary tuberculosis: the gateway of disease transmission
ME Urbanowski, AA Ordonez… - The Lancet Infectious …, 2020 - thelancet.com
Tuberculosis continues to be a major threat to global health. Cavitation is a dangerous
consequence of pulmonary tuberculosis associated with poor outcomes, treatment relapse …
consequence of pulmonary tuberculosis associated with poor outcomes, treatment relapse …