Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

Nucleolin (NCL) is a multifunctional protein that mainly localized in the nucleolus, it is also
found in the nucleoplasm, cytoplasm and cell membrane. The three main structural domains …

Nucleolin (NCL) is one of the most abundant non ribosomal protein of the nucleolus where it
plays a central role in polymerase I transcription. NCL is also found outside of the nucleolus …

Cell signaling mechanisms modulate gene expression in response to internal and external
stimuli. Cellular adaptation requires a precise and coordinated regulation of the transcription …

Many viruses shut off host gene expression to inhibit antiviral responses. Viral proteins and
host proteins required for viral replication are typically spared in this process, but the …

Objective—Macrophages play key roles in inflammation and diabetic vascular
complications. Emerging evidence implicates long noncoding RNAs in inflammation, but …

Nuclear-retained long non-coding RNAs (lncRNAs) including MALAT1 have emerged as
critical regulators of many molecular processes including transcription, alternative splicing …

The main localization of nucleolin is the nucleolus, but this protein is present in multiple
subcellular sites, and it is unconventionally secreted. On the cell surface, nucleolin acts as a …

Nucleolin, a multifunctional protein distributed in the nucleolus, participates in many
modulations including rDNA transcription, RNA metabolism, and ribosome assembly …

MALAT1, an abundant lncRNA specifically localized to nuclear speckles, regulates
alternative-splicing (AS). The molecular basis of its role in AS remains poorly understood …