Context Use of generic drugs, which are bioequivalent to brand-name drugs, can help
contain prescription drug spending. However, there is concern among patients and …

This meta-analysis aimed to compare the efficacy and adverse events, either serious or
mild/moderate, of all generic versus brand-name cardiovascular medicines. We searched …

Context Both benign prostatic hyperplasia (BPH) and cataract formation are common in
older men. The α-adrenergic receptor blocker tamsulosin is frequently prescribed to treat …

Complexes of copper (II), zinc (II), nickel (II), cobalt (II) and iron (III) with 4-methyl-7-
hydroxycoumarin sodium salt (Mendiaxon, Hymecromone) were synthesized by mixing of …

The use of generic drugs has become increasingly common in clinical practice. However, for
drugs with a narrow therapeutic index, such as warfarin, there may be some concern …

Objective Our objective was to examine possible changes in the effectiveness of warfarin
after a nationwide generic substitution of formulations in 1998. Methods In the computerized …

BACKGROUND: Substitution of generic warfarin for imprint warfarin (Coumadin;
DuPont/Bristol-Myers Squibb) has been a controversial issue due to bioavailability and …

BACKGROUND Warfarin is a commonly used anticoagulant in North America. Several
generic formulations have been approved, raising concern over the safety and efficacy of …

BACKGROUND: Substitution of generic warfarin for Coumadin presents safety concerns due
to warfarin's narrow therapeutic index and because a prior generic formulation was removed …

OBJECTIVE: To discuss the effect on the international normalized ratio (INR) when patients
are converted from therapy with Coumadin to generic warfarin. CASE SUMMARY: Two …