Spatial representation in the hippocampal formation: a history

EI Moser, MB Moser, BL McNaughton - Nature neuroscience, 2017 - nature.com
Since the first place cell was recorded and the cognitive-map theory was subsequently
formulated, investigation of spatial representation in the hippocampal formation has evolved …

A critical review of the allocentric spatial representation and its neural underpinnings: toward a network-based perspective

AD Ekstrom, AEGF Arnold, G Iaria - Frontiers in human neuroscience, 2014 - frontiersin.org
While the widely studied allocentric spatial representation holds a special status in
neuroscience research, its exact nature and neural underpinnings continue to be the topic of …

Integrating time from experience in the lateral entorhinal cortex

A Tsao, J Sugar, L Lu, C Wang, JJ Knierim, MB Moser… - Nature, 2018 - nature.com
The encoding of time and its binding to events are crucial for episodic memory, but how
these processes are carried out in hippocampal–entorhinal circuits is unclear. Here we …

[HTML][HTML] Anxiety cells in a hippocampal-hypothalamic circuit

JC Jimenez, K Su, AR Goldberg, VM Luna, JS Biane… - Neuron, 2018 - cell.com
The hippocampus is traditionally thought to transmit contextual information to limbic
structures where it acquires valence. Using freely moving calcium imaging and …

A prefrontal–thalamo–hippocampal circuit for goal-directed spatial navigation

HT Ito, SJ Zhang, MP Witter, EI Moser, MB Moser - Nature, 2015 - nature.com
Spatial navigation requires information about the relationship between current and future
positions. The activity of hippocampal neurons appears to reflect such a relationship …

[HTML][HTML] Sublayer-specific coding dynamics during spatial navigation and learning in hippocampal area CA1

NB Danielson, JD Zaremba, P Kaifosh, J Bowler… - Neuron, 2016 - cell.com
The mammalian hippocampus is critical for spatial information processing and episodic
memory. Its primary output cells, CA1 pyramidal cells (CA1 PCs), vary in genetics …

Object and spatial mnemonic interference differentially engage lateral and medial entorhinal cortex in humans

ZM Reagh, MA Yassa - Proceedings of the National …, 2014 - National Acad Sciences
Recent models of episodic memory propose a division of labor among medial temporal lobe
cortices comprising the parahippocampal gyrus. Specifically, perirhinal and lateral …

Hippocampal remapping as hidden state inference

H Sanders, MA Wilson, SJ Gershman - Elife, 2020 - elifesciences.org
Cells in the hippocampus tuned to spatial location (place cells) typically change their tuning
when an animal changes context, a phenomenon known as remapping. A fundamental …

Grid and nongrid cells in medial entorhinal cortex represent spatial location and environmental features with complementary coding schemes

GW Diehl, OJ Hon, S Leutgeb, JK Leutgeb - Neuron, 2017 - cell.com
The medial entorhinal cortex (mEC) has been identified as a hub for spatial information
processing by the discovery of grid, border, and head-direction cells. Here we find that in …

Social and novel contexts modify hippocampal CA2 representations of space

GM Alexander, S Farris, JR Pirone, C Zheng… - Nature …, 2016 - nature.com
The hippocampus supports a cognitive map of space and is critical for encoding declarative
memory (who, what, when and where). Recent studies have implicated hippocampal …