▪ Abstract About 20 years ago, DNA sequences were separately described from the quagga
(a type of zebra) and an ancient Egyptian individual. What made these DNA sequences …

In the past two decades, ancient DNA research has progressed from the retrieval of small
fragments of mitochondrial DNA from a few late Holocene specimens, to large-scale studies …

Claims of extreme survival of DNA have emphasized the need for reliable models of DNA
degradation through time. By analysing mitochondrial DNA (mtDNA) from 158 radiocarbon …

Mutational events along the human mtDNA phylogeny are traditionally identified relative to
the revised Cambridge Reference Sequence, a contemporary European sequence …

ABSTRACT DNA sequences determined from ancient organisms have high error rates,
primarily due to uracil bases created by cytosine deamination. We use synthetic …

Many species have undergone dramatic population size declines over the past centuries.
Although stochastic genetic processes during and after such declines are thought to elevate …

Lactase persistence (LP), the dominant Mendelian trait conferring the ability to digest the
milk sugar lactose in adults, has risen to high frequency in central and northern Europeans …

Background Poorly preserved biological tissues have become an important source of DNA
for a wide range of zoological studies. Measuring the quality of DNA obtained from these …

Mitochondrial DNA (mtDNA) sequences are commonly used for inferring phylogenetic
relationships. However, the strand-specific bias in the nucleotide composition of the mtDNA …

In the recent years, many protocols aimed at reproducibly sequencing reduced-genome
subsets in non-model organisms have been published. Among them, RAD-sequencing is …