Sample preparation is a crucial step for the reliable and accurate analysis of both small
molecule and biopolymers which often involves processes such as isolation, pre …

Nanoparticle scaffolds can impart multiple benefits onto immobilized enzymes including
enhanced stability, activity, and recoverability. The magnitude of these benefits is modulated …

Adsorption of proteins on nanoparticles is a complex and poorly studied process. The
mechanisms of protein layer formation can fundamentally differ depending on the …

Homogeneous immunoassays represent an attractive alternative to traditional
heterogeneous assays due to their simplicity, sensitivity, and speed. On the basis of a …

Functional enzyme–nanoparticle bioconjugates are increasingly important in biomedical
and biotechnology applications such as drug delivery and biosensing. Optimization of the …

It is of paramount importance to be able to accurately quantify surface coverage of
antibodies on gold nanoparticles (AuNP) so as to optimise the sensitivity of AuNP-based …

Nanoparticle-enhanced laser-induced breakdown spectroscopy (NELIBS) is an optical
emission technique based on the laser-induced plasma (LIP) on a sample after the …

Here we report on the use of heterobifunctional cross-linkers (HBCLs) to control the number,
orientation, and activity of immunoglobulin G antibodies (Abs) conjugated to silver …

Abstract Recently nanoparticle enhanced Laser Induced Breakdown Spectroscopy
(NELIBS) is getting a growing interest as an effective alternative method for improving the …

Direct measurements to determine the degree of surface coverage of nanoparticles by
functional moieties are rare, with current strategies requiring a high level of expertise and …