Diabetic neuropathy and neuropathic pain: a (con) fusion of pathogenic mechanisms?

NA Calcutt - Pain, 2020 - journals.lww.com
Neuropathy will afflict over half of the estimated 460 million people worldwide who have
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …

circRNAs signature as potential diagnostic and prognostic biomarker for diabetes mellitus and related cardiovascular complications

M Zaiou - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) belong to the ever-growing class of naturally occurring noncoding
RNAs (ncRNAs) molecules. Unlike linear RNA, circRNAs are covalently closed transcripts …

Epigenetic modifications in diabetes

RA Kowluru, G Mohammad - Metabolism, 2022 - Elsevier
Diabetes is now considered as a 'silent epidemic'that claims over four million lives every
year, and the disease knows no socioeconomic boundaries. Despite extensive efforts by the …

Role of miRNAs in diabetic neuropathy: mechanisms and possible interventions

P Kaur, S Kotru, S Singh, A Munshi - Molecular neurobiology, 2022 - Springer
Accelerating cases of diabetes worldwide have given rise to higher incidences of diabetic
complications. MiRNAs, a much-explored class of non-coding RNAs, play a significant role …

MicroRNA 21 emerging role in diabetic complications: a critical update

D Roy, A Modi, M Khokhar… - Current diabetes …, 2021 - ingentaconnect.com
Background: Diabetes Mellitus is a multifactorial disease encompassing various pathogenic
pathways. To avoid morbidity and mortality related to diabetic complications, early detection …

Genetic and epigenomic modifiers of diabetic neuropathy

M Jankovic, I Novakovic, D Nikolic… - International journal of …, 2021 - mdpi.com
Diabetic neuropathy (DN), the most common chronic and progressive complication of
diabetes mellitus (DM), strongly affects patients' quality of life. DN could be present as …

Determination of the transcriptional level of long non-coding RNA NEAT-1, downstream target microRNAs, and genes targeted by microRNAs in diabetic neuropathy …

G Asadi, FR Varmaziar, M Karimi, M Rajabinejad… - Immunology letters, 2021 - Elsevier
Background Diabetic neuropathy (DN) is one of the microvascular complications of diabetes
that leads to peripheral sensorimotor and autonomic nervous system damages. In this study …

Quercetin‑conjugated superparamagnetic iron oxide nanoparticles modulate glucose metabolism-related genes and miR-29 family in the hippocampus of diabetic rats

S Dini, M Zakeri, S Ebrahimpour, F Dehghanian… - Scientific Reports, 2021 - nature.com
Quercetin (QC) is a dietary bioflavonoid that can be conjugated with nanoparticles to
facilitate its brain bioavailability. We previously showed that quercetin-conjugated …

[HTML][HTML] Emerging roles of microRNAs as biomarkers and therapeutic targets for diabetic neuropathy

B Fan, M Chopp, ZG Zhang, XS Liu - Frontiers in Neurology, 2020 - frontiersin.org
Diabetic neuropathy (DN) is the most prevalent chronic complication of diabetes mellitus.
The exact pathophysiological mechanisms of DN are unclear; however, communication …

MicroRNAs and risk factors for diabetic nephropathy in Egyptian children and adolescents with type 1 diabetes

S Abdelghaffar, H Shora, S Abdelatty… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Purpose Currently available markers for early detection of diabetic nephropathy (DN), the
leading cause of end stage renal disease, have some limitations. There is insufficient …