The rising era of “Immunoporosis”: Role of immune system in the pathophysiology of osteoporosis

RK Srivastava, L Sapra - Journal of Inflammation Research, 2022 - Taylor & Francis
Discoveries in the last few years have emphasized the existence of an enormous breadth of
communication between bone and the immune system in maintaining skeletal homeostasis …

[HTML][HTML] Long-term implications of COVID-19 on bone health: pathophysiology and therapeutics

L Sapra, C Saini, B Garg, R Gupta, B Verma… - Inflammation …, 2022 - Springer
Background SARS-CoV-2 is a highly infectious respiratory virus associated with coronavirus
disease (COVID-19). Discoveries in the field revealed that inflammatory conditions exert a …

[HTML][HTML] Moringa oleifera leaf attenuate osteoporosis in ovariectomized rats by modulating gut microbiota composition and MAPK signaling pathway

XH Hu, XY Yang, J Lian, Y Chen, CY Zheng… - Biomedicine & …, 2023 - Elsevier
Moringa oleifera leaf (MLP) contains abundant complex nutrients with anti-osteoporosis
potential. However, its efficacy and mechanisms against osteoporosis remain unknown. The …

[HTML][HTML] Linking the relation between gut microbiota and glucocorticoid-induced osteoporosis

RX Zhou, YW Zhang, MM Cao, CH Liu, YF Rui… - Journal of Bone and …, 2023 - Springer
Osteoporosis (OP) is the most prevalent metabolic bone disease, characterized by the low
bone mass and microarchitectural deterioration of bone tissue. Glucocorticoid (GC) clinically …

[HTML][HTML] Bile acid metabolism regulatory network orchestrates bone homeostasis

T Xiang, Z Deng, C Yang, J Tan, C Dou, F Luo… - Pharmacological …, 2023 - Elsevier
Bile acids (BAs), synthesized in the liver and modified by the gut microbiota, have been
widely appreciated not only as simple lipid emulsifiers, but also as complex metabolic …

[HTML][HTML] Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by …

J Tang, X Song, M Zhao, H Chen, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Osteoarthritis (OA) causes intestinal damage. The protective effect of probiotics on the
intestine is indeed effective; however, the mechanism of protection against intestinal …

[HTML][HTML] Low Ca diet leads to increased Ca retention by changing the gut flora and ileal pH value in laying hens

S Jiang, X Zou, M Mao, M Zhang, W Tu, M Jin - Animal Nutrition, 2023 - Elsevier
Osteoporosis is a common degenerative metabolic bone disease in caged laying hens.
Intensive egg production mobilizing large amounts of Ca from bone for eggshell formation …

[HTML][HTML] Roles of gut microbiome in bone homeostasis and its relationship with bone-related diseases

N Zemanova, R Omelka, V Mondockova, V Kovacova… - Biology, 2022 - mdpi.com
Simple Summary In recent years, there has been increasing evidence that communication
between the skeletal system and the gut microbiome (GM) can influence bone health and …

Fine‐tuning osteoclastogenesis: An insight into the cellular and molecular regulation of osteoclastogenesis

A Anwar, L Sapra, N Gupta, RP Ojha… - Journal of cellular …, 2023 - Wiley Online Library
Osteoclasts, the bone‐resorbing cells, are essential for the bone remodeling process and
are involved in the pathophysiology of several bone‐related diseases. The extensive corpus …

Lactobacillus rhamnosus (LR) ameliorates pulmonary and extrapulmonary acute respiratory distress syndrome (ARDS) via targeting neutrophils

L Sapra, C Saini, S Das, PK Mishra, A Singh… - Clinical …, 2024 - Elsevier
Pulmonary and extrapulmonary acute respiratory distress syndrome (ARDS) is a life-
threatening respiratory failure associated with high mortality. Despite progress in our …