Hormonal axes in Drosophila: regulation of hormone release and multiplicity of actions

DR Nässel, M Zandawala - Cell and tissue research, 2020 - Springer
Hormones regulate development, as well as many vital processes in the daily life of an
animal. Many of these hormones are peptides that act at a higher hierarchical level in the …

G-protein coupled receptors (GPCRs): signaling pathways, characterization, and functions in insect physiology and toxicology

N Liu, Y Wang, T Li, X Feng - International Journal of Molecular Sciences, 2021 - mdpi.com
G-protein-coupled receptors (GPCRs) are known to play central roles in the physiology of
many organisms. Members of this seven α-helical transmembrane protein family transduce …

[HTML][HTML] Impact of high-fat diet on lifespan, metabolism, fecundity and behavioral senescence in Drosophila

S Liao, M Amcoff, DR Nässel - Insect biochemistry and molecular biology, 2021 - Elsevier
Excess consumption of high-fat diet (HFD) is likely to result in obesity and increases the
predisposition to associated health disorders. Drosophila melanogaster has emerged as an …

G-protein coupled receptors (GPCRs) in insects—A potential target for new insecticide development

N Liu, T Li, Y Wang, S Liu - Molecules, 2021 - mdpi.com
G-protein coupled receptors (GPCRs) play important roles in cell biology and insects'
physiological processes, toxicological response and the development of insecticide …

G protein-coupled receptors function as cell membrane receptors for the steroid hormone 20-hydroxyecdysone

XF Zhao - Cell Communication and Signaling, 2020 - Springer
G protein-coupled receptors (GPCRs) are cell membrane receptors for various ligands.
Recent studies have suggested that GPCRs transmit animal steroid hormone signals …

Voluntary intake of psychoactive substances is regulated by the dopamine receptor Dop1R1 in Drosophila

M Kanno, S Hiramatsu, S Kondo, H Tanimoto… - Scientific reports, 2021 - nature.com
Dysregulated motivation to consume psychoactive substances leads to addictive behaviors
that often result in serious health consequences. Understanding the neuronal mechanisms …

Mild traumatic brain injury in Drosophila melanogaster alters reactive oxygen and nitrogen species in a sex-dependent manner

TB Jones, T Mackey, AN Juba, K Amin, A Atyam… - Experimental …, 2024 - Elsevier
Traumatic brain injury (TBI) is an outside force causing a modification in brain function
and/or structural brain pathology that upregulates brain inducible nitric oxide synthase …

[HTML][HTML] Advancements in the impact of insect gut microbiota on host feeding behaviors

Y Wang, L Wang, D Li, Z Chen, Y Luo, J Zhou, B Luo… - Genes, 2024 - mdpi.com
With the application and development of high-throughput sequencing technology, the
structure and function of insect gut microbiota have been analysed, which lays a foundation …

Rethinking the ecdysteroid source during Drosophila pupal–adult development

JL Scanlan, C Robin, CK Mirth - Insect Biochemistry and Molecular Biology, 2023 - Elsevier
Abstract Ecdysteroids, typified by 20-hydroxyecdysone (20E), are essential hormones for the
development, reproduction and physiology of insects and other arthropods. For over half a …

A cell atlas of the larval Aedes aegypti ventral nerve cord

C Yin, T Morita, JZ Parrish - Neural Development, 2024 - Springer
Mosquito-borne diseases account for nearly 1 million human deaths annually, yet we have a
limited understanding of developmental events that influence host-seeking behavior and …