[HTML][HTML] Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior

MR Picciotto, MJ Higley, YS Mineur - Neuron, 2012 - cell.com
Acetylcholine in the brain alters neuronal excitability, influences synaptic transmission,
induces synaptic plasticity, and coordinates firing of groups of neurons. As a result, it …

The posterior crus II cerebellum is specialized for social mentalizing and emotional self-experiences: a meta-analysis

F Van Overwalle, Q Ma… - Social cognitive and …, 2020 - academic.oup.com
This meta-analysis explores the role of the posterior cerebellum Crus I/II in social
mentalizing. We identified over 200 functional magnetic resonance imaging (fMRI) studies …

Midbrain dopamine neurons bidirectionally regulate CA3-CA1 synaptic drive

ZB Rosen, S Cheung, SA Siegelbaum - Nature neuroscience, 2015 - nature.com
Dopamine (DA) is required for hippocampal-dependent memory and long-term potentiation
(LTP) at CA1 Schaffer collateral (SC) synapses. It is therefore surprising that exogenously …

Load modulation of BOLD response and connectivity predicts working memory performance in younger and older adults

IE Nagel, C Preuschhof, SC Li, L Nyberg… - Journal of Cognitive …, 2011 - direct.mit.edu
Individual differences in working memory (WM) performance have rarely been related to
individual differences in the functional responsivity of the WM brain network. By neglecting …

Modulation, plasticity and pathophysiology of the parallel fiber-purkinje cell synapse

E Hoxha, F Tempia, P Lippiello… - Frontiers in synaptic …, 2016 - frontiersin.org
The parallel fiber-Purkinje cell (PF-PC) synapse represents the point of maximal signal
divergence in the cerebellar cortex with an estimated number of about 60 billion synaptic …

Neurochemistry of visual attention

DEL Lockhofen, C Mulert - Frontiers in neuroscience, 2021 - frontiersin.org
Visual attention is the cognitive process that mediates the selection of important information
from the environment. This selection is usually controlled by bottom-up and top-down …

Neuromodulators and long-term synaptic plasticity in learning and memory: A steered-glutamatergic perspective

AH Bazzari, HR Parri - Brain sciences, 2019 - mdpi.com
The molecular pathways underlying the induction and maintenance of long-term synaptic
plasticity have been extensively investigated revealing various mechanisms by which …

Beyond the wiring diagram: signalling through complex neuromodulator networks

V Brezina - … Transactions of the Royal Society B …, 2010 - royalsocietypublishing.org
During the computations performed by the nervous system, its 'wiring diagram'—the map of
its neurons and synaptic connections—is dynamically modified and supplemented by …

Functional division of hippocampal area CA1 via modulatory gating of entorhinal cortical inputs

HT Ito, EM Schuman - Hippocampus, 2012 - Wiley Online Library
The hippocampus receives two streams of information, spatial and nonspatial, via major
afferent inputs from the medial (MEC) and lateral entorhinal cortexes (LEC). The MEC and …

Dopamine regulates intrinsic excitability thereby gating successful induction of spike timing-dependent plasticity in CA1 of the hippocampus

E Edelmann, V Lessmann - Frontiers in neuroscience, 2013 - frontiersin.org
Long-term potentiation (LTP) and long-term depression (LTD) are generally assumed to be
cellular correlates for learning and memory. Different types of LTP induction protocols …