Population management using gene drive: molecular design, models of spread dynamics and assessment of ecological risks
CRISPR gene drive has recently been proposed as a promising technology for population
management, including in conservation genetics. The technique would consist in releasing …
management, including in conservation genetics. The technique would consist in releasing …
Development of a confinable gene drive system in the human disease vector Aedes aegypti
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …
millions of people every year. With an escalating burden of infections and the relative failure …
Molecular safeguarding of CRISPR gene drive experiments
CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due
to their potential for genetically altering entire species. This raises the question about our …
to their potential for genetically altering entire species. This raises the question about our …
Gene Drives as Interventions into Nature: the Coproduction of Ontology and Morality in the Gene Drive Debate
Gene drives are potentially ontologically and morally disruptive technologies. The potential
to shape evolutionary processes and to eradicate (eg malaria-transmitting or invasive) …
to shape evolutionary processes and to eradicate (eg malaria-transmitting or invasive) …
What can genetic association panels tell us about evolutionary processes in insects?
Highlights•Genetic association panels provide a focus for research community
efforts.•Genetic association panels unite genetic variation and systems biology.•The overlap …
efforts.•Genetic association panels unite genetic variation and systems biology.•The overlap …
[PDF][PDF] Molecular safeguarding of CRISPR gene drive experiments
CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due
to their potential for genetically altering entire species. This raises the question about our …
to their potential for genetically altering entire species. This raises the question about our …