Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …

Visualizing the structure and dynamics of biomolecules is critical to understand biological
function, and requires methods to fluorescently label targets of interest in their cellular …

Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However …

Monitoring spiking activity across large neuronal populations at behaviorally relevant
timescales is critical for understanding neural circuit function. Unlike calcium imaging …

The ability to optically image cellular transmembrane voltages at millisecond-timescale
resolutions can offer unprecedented insight into the function of living brains in behaving …

Rhodopsins had long been considered non-fluorescent until a peculiar voltage-sensitive
fluorescence was reported for archaerhodopsin-3 (Arch3) derivatives. These proteins …

Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …

Voltage imaging measures neuronal activity directly and holds promise for understanding
information processing within individual neurons and across populations. However, imaging …

Monitoring neural activity in individual neurons is crucial for understanding neural circuits
and brain functions. The emergence of optical imaging technologies has dramatically …