Dimensionality reduction for large-scale neural recordings

JP Cunningham, BM Yu - Nature neuroscience, 2014 - nature.com
Most sensory, cognitive and motor functions depend on the interactions of many neurons. In
recent years, there has been rapid development and increasing use of technologies for …

[HTML][HTML] The Dimensions of dimensionality

BD Roads, BC Love - Trends in Cognitive Sciences, 2024 - cell.com
Cognitive scientists often infer multidimensional representations from data. Whether the data
involve text, neuroimaging, neural networks, or human judgments, researchers frequently …

Demixed principal component analysis of neural population data

D Kobak, W Brendel, C Constantinidis, CE Feierstein… - elife, 2016 - elifesciences.org
Neurons in higher cortical areas, such as the prefrontal cortex, are often tuned to a variety of
sensory and motor variables, and are therefore said to display mixed selectivity. This …

[PDF][PDF] Linear dimensionality reduction: Survey, insights, and generalizations

JP Cunningham, Z Ghahramani - The Journal of Machine Learning …, 2015 - jmlr.org
Linear dimensionality reduction methods are a cornerstone of analyzing high dimensional
data, due to their simple geometric interpretations and typically attractive computational …

Stable population coding for working memory coexists with heterogeneous neural dynamics in prefrontal cortex

JD Murray, A Bernacchia, NA Roy… - Proceedings of the …, 2017 - National Acad Sciences
Working memory (WM) is a cognitive function for temporary maintenance and manipulation
of information, which requires conversion of stimulus-driven signals into internal …

[HTML][HTML] Accurate estimation of neural population dynamics without spike sorting

EM Trautmann, SD Stavisky, S Lahiri, KC Ames… - Neuron, 2019 - cell.com
A central goal of systems neuroscience is to relate an organism's neural activity to behavior.
Neural population analyses often reduce the data dimensionality to focus on relevant activity …

Independent generation of sequence elements by motor cortex

AJ Zimnik, MM Churchland - Nature neuroscience, 2021 - nature.com
Rapid execution of motor sequences is believed to depend on fusing movement elements
into cohesive units that are executed holistically. We sought to determine the contribution of …

The largest response component in the motor cortex reflects movement timing but not movement type

MT Kaufman, JS Seely, D Sussillo, SI Ryu, KV Shenoy… - eneuro, 2016 - eneuro.org
Neural activity in monkey motor cortex (M1) and dorsal premotor cortex (PMd) can reflect a
chosen movement well before that movement begins. The pattern of neural activity then …

Computing by robust transience: how the fronto-parietal network performs sequential, category-based decisions

W Chaisangmongkon, SK Swaminathan, DJ Freedman… - Neuron, 2017 - cell.com
Decision making involves dynamic interplay between internal judgements and external
perception, which has been investigated in delayed match-to-category (DMC) experiments …

Variational latent gaussian process for recovering single-trial dynamics from population spike trains

Y Zhao, IM Park - Neural computation, 2017 - direct.mit.edu
When governed by underlying low-dimensional dynamics, the interdependence of
simultaneously recorded populations of neurons can be explained by a small number of …