Global impacts of western diet and its effects on metabolism and health: A narrative review

VJ Clemente-Suárez, AI Beltrán-Velasco… - Nutrients, 2023 - mdpi.com
The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged
foods, refined grains, red meat, processed meat, high-sugar drinks, candy, sweets, fried …

Immunology of aging: the birth of inflammaging

T Fulop, A Larbi, G Pawelec, A Khalil, AA Cohen… - Clinical reviews in …, 2021 - Springer
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

Oxidative stress, aging, antioxidant supplementation and their impact on human health: An overview

G Martemucci, P Portincasa, A Di Ciaula… - Mechanisms of Ageing …, 2022 - Elsevier
Aging is characterized by a progressive loss of tissue and organ function due to genetic and
environmental factors, nutrition, and lifestyle. Oxidative stress is one the most important …

Mitochondrial stress and mitokines in aging

J Burtscher, A Soltany, NP Visavadiya, M Burtscher… - Aging …, 2023 - Wiley Online Library
Mitokines are signaling molecules that enable communication of local mitochondrial stress
to other mitochondria in distant cells and tissues. Among those molecules are FGF21 …

[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation

CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

Understanding long COVID; mitochondrial health and adaptation—old pathways, new problems

AVW Nunn, GW Guy, W Brysch, JD Bell - Biomedicines, 2022 - mdpi.com
Many people infected with the SARS-CoV-2 suffer long-term symptoms, such as “brain fog”,
fatigue and clotting problems. Explanations for “long COVID” include immune imbalance …

The muscle-brain axis and neurodegenerative diseases: the key role of mitochondria in exercise-induced neuroprotection

J Burtscher, GP Millet, N Place, B Kayser… - International Journal of …, 2021 - mdpi.com
Regular exercise is associated with pronounced health benefits. The molecular processes
involved in physiological adaptations to exercise are best understood in skeletal muscle …

The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis

S Lenhard, S Gerlich, A Khan, S Rödl… - Journal of Cell …, 2023 - rupress.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) expresses high
amounts of the protein Orf9b to target the mitochondrial outer membrane protein Tom70 …

Metabolic health, mitochondrial fitness, physical activity, and cancer

VJ Clemente-Suárez, A Martín-Rodríguez… - Cancers, 2023 - mdpi.com
Simple Summary Recent research suggests a strong link between the functioning of
mitochondria and the development of cancer. Healthy mitochondria play a vital role in …

[HTML][HTML] Immune consequences of exercise in hypoxia: a narrative review

J Burtscher, Q Pasha, N Chanana, GP Millet… - Journal of Sport and …, 2024 - Elsevier
Immune outcomes are key mediators of many health benefits of exercise and are
determined by exercise type, dose (frequency/duration, intensity), and individual …