Background Antimicrobial resistance is an emerging problem worldwide and poses a
significant threat to human health. Antimicrobial stewardship programmes are being …

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The adverse effects of azithromycin on the treatment of patients with chronic lung diseases
(CLD) were evaluated in the present study. MEDLINE and other databases were searched …

The human microbiome, which consists of a collective cluster of commensal, symbiotic, and
pathogenic microorganisms living in the human body, plays a key role in host health and …

Background: Among First Nations adults living in OECD nations bronchiectasis appears at a
particularly heightened rate, due to high childhood incidence, and high prevalence of …

Although long-term azithromycin decreases exacerbation frequency in bronchiectasis,
increased macrolide resistance is concerning. We investigated macrolide resistance …

Background: High-level evidence is limited for antibiotic duration in children hospitalized
with community-acquired pneumonia (CAP) from First Nations and other at-risk populations …

The term respiratory disease refers to a number of conditions that affect the lungs or their
components [1]; each of these conditions is characterised by some level of impairment of the …

Recent clinical trials indicate that the use of azithromycin is associated with the emergence
of macrolide resistance. The objective of our study was to simultaneously characterize free …

BACKGROUND Acute respiratory exacerbations (AREs) cause morbidity and lung function
decline in children with chronic suppurative lung disease (CSLD) and bronchiectasis. In a …