Aim To evaluate gastrointestinal motility during 5-fluorouracil (5-FU)-induced intestinal
mucositis. Materials and methods Wistar rats received 5-FU (150 mg kg− 1, ip) or saline …

Aim The aim of this study was to evaluate the effect of telmisartan (TELM) on inflammation,
oxidation and the expression of matrix metalloproteinases (MMP s) and the expression …

Aim To evaluate the anti-inflammatory, anti-oxidant and antifibrotic effects of carvedilol
(CARV) in rats with ethanol-induced liver injury. Methods Liver injury was induced by …

Introduction Mucositis induced by antineoplastic drugs is an important, dose-limiting, and
costly side effect of cancer therapy. Aim: To investigate the role of nitric oxide (NO) on the …

Eucalyptol, also known as 1, 8‐cineole, is a monoterpene traditionally used to treat
respiratory disorders due to its secretolytic properties. In addition to its myorelaxant effects, it …

Background Methotrexate treatment has been associated to intestinal epithelial damage.
Studies have suggested an important role of nitric oxide in such injury. The aim of this study …

Dipyrone (metamizole), acting through its main metabolites 4-methyl-amino-antipyrine and 4-
amino-antipyrine, has established analgesic, antipyretic, and spasmolytic pharmacological …

Objective The aim of this study was to evaluate the effects of gliclazide on oxidative stress,
inflammation, and bone loss in an experimental periodontal disease model. Material and …

Periodontal diseases are initiated primarily by Gram-negative, tooth-associated microbial
biofilms that elicit a host response that causes osseous and soft tissue destruction …

Oral mucositis (OM) is a common complication of treatments for head and neck cancer,
particularly radiotherapy with or without chemotherapy. OM is characterised by oral …