Recent advances in systemic therapy for hepatocellular carcinoma

H Zhang, W Zhang, L Jiang, Y Chen - Biomarker Research, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in
the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially …

[HTML][HTML] Angiogenesis in hepatocellular carcinoma: mechanisms and anti-angiogenic therapies

C Yao, S Wu, J Kong, Y Sun, Y Bai, R Zhu… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-associated death
worldwide. Angiogenesis, the process of formation of new blood vessels, is required for …

The impact of periodontitis on vascular endothelial dysfunction

Q Li, X Ouyang, J Lin - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
Periodontitis, an oral inflammatory disease, originates from periodontal microbiota dysbiosis
which is associated with the dysregulation of host immunoinflammatory response. This …

The cardiac glycoside deslanoside exerts anticancer activity in prostate cancer cells by modulating multiple signaling pathways

M Liu, Q Huang, L Li, X Li, Z Zhang, JT Dong - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer is a leading cause of cancer-related deaths among men,
and novel therapies for advanced PCa are urgently needed. Cardiac glycosides are a group …

CD105: tumor diagnosis, prognostic marker and future tumor therapeutic target

L Li, L Zhong, C Tang, L Gan, T Mo, J Na, J He… - Clinical and …, 2022 - Springer
Cancer is one of the diseases with the highest morbidity and mortality rates worldwide, and
its therapeutic options are inadequate. The endothelial glycoprotein, also known as CD105 …

Unveiling heterogeneity in MSCs: exploring marker-based strategies for defining MSC subpopulations

S Chen, B Liang, J Xu - Journal of Translational Medicine, 2024 - Springer
Mesenchymal stem/stromal cells (MSCs) represent a heterogeneous cell population
distributed throughout various tissues, demonstrating remarkable adaptability to …

Tumoral CD105 promotes immunosuppression, metastasis, and angiogenesis in renal cell carcinoma

M Oladejo, HM Nguyen, H Seah, A Datta… - Cancer Immunology …, 2023 - Springer
CD105 (endoglin) is a transmembrane protein that functions as a TGF-beta coreceptor and
is highly expressed on endothelial cells. Unsurprisingly, preclinical and clinical evidence …

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling

Q Huang, R Xiao, J Lu, Y Zhang, L Xu, J Gao… - Frontiers in …, 2022 - frontiersin.org
Background: Peritoneal fibrosis (PF) is an intractable complication in patients on long-term
peritoneal dialysis (PD). Transforming growth factor-β (TGF-β) is a key pro-fibrogenic factor …

[HTML][HTML] Significance of Immune and Non-Immune Cell Stroma as a Microenvironment of Hepatocellular Carcinoma—From Inflammation to Hepatocellular Carcinoma …

J Baj, M Kołodziej, J Kobak, J Januszewski… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common liver cancer as well as the most
prevalent cause of death in the adult patient population with cirrhosis. The occurrence of …

High Procalcitonin, C-Reactive Protein, and α-1 Acid Glycoprotein Levels in Whole Blood Samples Could Help Rapid Discrimination of Active Tuberculosis from Latent …

YJ Kang, H Park, SB Park, J Lee, H Hyun, M Jung… - Microorganisms, 2022 - mdpi.com
Tuberculosis (TB) management is important for prompt discrimination of latent TB infection
(LTBI) from active TB and proper treatment. Whole blood Interferon-gamma (IFN-γ) release …