Purpose To compare international and regional guidelines for prescription and monitoring of
response to biologics in chronic rhinosinusitis with nasal polyps (CRSwNP). Methods A …

Introduction The introduction of biotherapies has significantly changed the management of
patients with chronic rhinosinusitis with nasal polyps (CRSwNP). These drugs are generally …

Allergic fungal rhinosinusitis (AFRS) is a highly resistant disease and is challenging to treat.
Patients with recurrent attacks of the disease despite surgical management can benefit from …

Abstract Introduction Biologic therapies for Chronic Rhinosinusitis with Nasal Polyps
(CRSwNP) have emerged as an auspicious treatment alternative. However, the ideal patient …

Background: Chronic rhinosinusitis (CRS) is a complex inflammatory disorder affecting the
nasal and paranasal sinuses. Mitophagy, the process of selective mitochondrial degradation …

In recent years, there has been growing interest in understanding the potential role of
microbiota dysbiosis or alterations in the composition and function of human microbiota in …

Background Chronic rhinosinusitis (CRS) is a heterogeneous disorder with a wide range of
validated subjective and objective assessment tools to assess disease severity. However, a …

Severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is a disabling airway disease
that significantly impacts patients' lives through the severity of symptoms, the need for long …

Aims Benralizumab, a humanized, afucosylated monoclonal antibody against the interleukin
5 receptor, α subunit, causes rapid depletion of eosinophils by antibody‐dependent cellular …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic and often debilitating
inflammatory condition of the nasal and paranasal tissues. An expert panel of specialists …