Depression is one of the leading causes of disability, and, if left unmanaged, it can increase
the risk for suicide. The evidence base on the determinants of depression is fragmented …

The aryl hydrocarbon receptor (AHR) is a nuclear receptor that modulates the response to
environmental stimuli. It was recognized historically for its role in toxicology but, in recent …

The increasing application of Artificial Intelligence (AI) in health and medicine has attracted
a great deal of research interest in recent decades. This study aims to provide a global and …

The gut microbiota is a complex and dynamic ecosystem essential for the proper functioning
of the organism, affecting the health and disease status of the individuals. There is …

The aryl hydrocarbon receptor (or AhR) is a cytoplasmic receptor of pollutants. It translocates
into the nucleus upon binding to its ligands, and forms a heterodimer with ARNT (AhR …

Background Major depressive disorder (MDD) is a highly heterogenous disease, both in
terms of clinical profiles and pathobiological alterations. Recently, immunometabolic …

The gut microbiota has been increasingly correlated with depressive disorder. It was
recently shown that the transplantation of the gut microbiota from depressed patients to …

It is unknown whether indoles, metabolites of tryptophan that are derived entirely from
bacterial metabolism in the gut, are associated with symptoms of depression and anxiety …

Combination antidepressant pharmacotherapies are frequently used to treat major
depressive disorder (MDD). However, there is no evidence that machine learning …

BACKGROUND: Dilated cardiomyopathy (DCM) is a major cause of heart failure and carries
a high mortality rate. Myocardial recovery in DCM-related heart failure patients is highly …