The Amaryllidaceae alkaloids: An untapped source of acetylcholinesterase inhibitors

S Berkov, M Atanasova, B Georgiev, J Bastida… - Phytochemistry …, 2021 - Springer
The AChE inhibitory activity of alkaloid extracts and compounds has been in the focus of
research on the plants of Amaryllidoideae subfamily since the approval of galanthamine in …

Biological activities of snowdrop (Galanthus spp., Family Amaryllidaceae)

CK Kong, LE Low, WS Siew, WH Yap… - Frontiers in …, 2021 - frontiersin.org
Snowdrop is an iconic early spring flowering plant of the genus Galanthus (Amaryllidaceae).
Galanthus species (Galanthus spp.) are economically important plants as ornaments …

[HTML][HTML] Neuroprotective effects of allocryptopine-rich alkaloid extracts against oxidative stress-induced neuronal damage

SN Dolanbay, FG Kocanci, B Aslim - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Background Oxidative stress is a significant feature in the pathomechanism of
neurodegenerative diseases. Thus, the search for an effective and safe novel antioxidant …

Application of in vivo solid phase microextraction (SPME) in capturing metabolome of apple (Malus ×domestica Borkh.) fruit

S Risticevic, EA Souza-Silva, E Gionfriddo, JR DeEll… - Scientific Reports, 2020 - nature.com
An in vivo direct-immersion SPME sampling coupled to comprehensive two-dimensional gas
chromatography–time-of-flight mass spectrometry (GCxGC-ToFMS) was employed to …

Cocktail of three isoquinoline alkaloids derived from Glaucium grandiflorum Boiss. & A. Huet subsp. refractum (Nábelek) Mory inhibits the production of LPS-induced …

SN Dolanbay, S Şirin, B Aslim - Fitoterapia, 2023 - Elsevier
Glaucium grandiflorum extracts have traditionally been used to treat brain-related disorders.
G. grandiflorum extracts also exhibited inhibitory effects on cholinesterase enzymes, as well …

[HTML][HTML] Alkaloid profiling, anticholinesterase activity and molecular modeling study of Galanthus elwesii

B Bozkurt, G Coban, GI Kaya, MA Onur… - South African Journal of …, 2017 - Elsevier
In this study, Galanthus elwesii Hook.(Amaryllidaceae) was investigated for its chemical
composition by using GC-MS (Gas Chromatography-Mass Spectrometry) method and …

Chemical profile, acetylcholinesterase, butyrylcholinesterase, and prolyl oligopeptidase inhibitory activity of Glaucium corniculatum subsp. refractum

B Bozkurt, D Ulkar, N Nurlu, GI Kaya… - Brazilian Journal of …, 2022 - SciELO Brasil
Papaveraceae is one of the prominent alkaloid-containing families, and plants of the genus
Glaucium (Papaveraceae) are known for their bioactive alkaloids. Glaucium species have …

Enhancing extraction efficiency of carpaine in Carica papaya L. leaves: coupling acid-base extraction with surfactant-assisted micro-flotation

TQ Lam, ATQ Tran, TLA Phan, F Zitzmann, NVH Phan… - RSC …, 2024 - pubs.rsc.org
Carpaine, a major alkaloid in papaya leaves, has considerable cardiovascular benefits
alongside its notable effects on muscle relaxation when utilized in medicine. In this study …

[HTML][HTML] Chemical characterization and biological activity of an endemic Amaryllidaceae species: Galanthus cilicicus

GI Kaya, K Uzun, B Bozkurt, MA Onur, NU Somer… - South African Journal of …, 2017 - Elsevier
The phytochemical investigation on Galanthus cilicicus Baker (Amaryllidaceae) led to the
isolation of four alkaloids (tazettine 1, galanthamine 2, sanguinine 3, and haemanthamine …

Neuroprotective Potential of Isoquinoline Alkaloids from Glaucium grandiflorum Boiss. and A. Huet subsp. refractum (Nábelek) Mory: Role of NRF2-KEAP1 Pathway

S Niğdelioğlu Dolanbay, S Şirin, B Aslim - Applied Sciences, 2023 - mdpi.com
The extracts of Glaucium grandiflorum have been used to treat neurodegenerative diseases.
Nonetheless, no former study has investigated whether the alkaloid extracts of G …