Actin, one of the main proteins of muscle and cytoskeleton, exists as a vaiety of highly
conserved isoforms whose distribution in vertebrates is tissue-specific. Synthesis of specific …

Actin is one of the most abundant proteins in nature. It is found in all eukaryotes and plays a
fundamental role in many diverse and dynamic cellular processes. Also, actin is one of the …

Using a reconstituted complex of profilin and skeletal muscle actin as an antigen, we
generated a monoclonal mouse antibody against actin, termed 2G2. As revealed by …

The vasodilator-stimulated phosphoprotein (VASP) functions as a cellular regulator of actin
dynamics. VASP may initialise actin polymerisation, suggesting a direct interaction with …

Using proteolytic susceptibility as a probe, we have identified four regions of the actin
polypeptide chain where structural rearrangements, dependent on the nature of the tightly …

Beryllium fluoride (BeFx) has been widely used as a phosphate analogue in nucleotide-
binding proteins. It was found to bind tightly to F-but not G-actin (Combeau C., and Carlier …

The biochemical properties of G-actin, and the kinetics of polymerization of G-actin into F-
actin, are dependent upon whether Mg2+ or Ca2+ is bound at the high-affinity metal-binding …

Porphyromonas gingivalis, a Gram‐negative oral pathogen, has been shown to induce
apoptosis in human gingival epithelial cells, yet the underlining cellular mechanisms …

Earlier, we have shown that spontaneously isolated non‐pathogenic bacteria Serratia
grimesii and Serratia proteamaculans invade eukaryotic cells, provided that they synthesize …

Protealysin is a thermolysin‐like protease of Serratia proteamaculans capable of specifically
cleaving actin, which correlates with the invasive activity of these bacteria. Here, we show …