In the last 5 years, most of the molecules that control mitochondrial Ca2+ homeostasis have
been finally identified. Mitochondrial Ca2+ uptake is mediated by the Mitochondrial Calcium …

Abstract Calcium (Ca 2+) signaling is critical for cell function and cell survival. Mitochondria
play a major role in regulating the intracellular Ca 2+ concentration ([Ca 2+] i). Mitochondrial …

The endoplasmic reticulum (ER) and mitochondria accumulate Ca2+ within their lumens to
regulate numerous cell functions. However, determining the dynamics of intraorganellar …

Juxtaposition between endoplasmic reticulum (ER) and mitochondria is a common structural
feature, providing the physical basis for intercommunication during Ca2+ signalling; yet, the …

The interplay between Ca 2+ and reactive oxygen species (ROS) signaling pathways is well
established, with reciprocal regulation occurring at a number of subcellular locations. Many …

Mitochondria are central to energy metabolism as the source of much of the cell's ATP, as
well as being a hub for cellular Ca 2+ signaling. Mitochondrial Ca 2+ is a positive effector of …

В работе представлен анализ литературы, синтез результатов экспериментальных и
клинических исследований, а также современное представление о механизмах …

Genetically encoded Ca2+ indicators allow researchers to quantitatively measure Ca2+
dynamics in a variety of experimental systems. This protocol summarizes the indicators that …

В основу книги легли ответы на многочисленные вопросы слушателей
специализированных курсов по программе «Лазерная медицина». Впервые сделан …

Background Spatial compartmentalization of metabolic pathways within membrane-
separated organelles is key to the ability of eukaryotic cells to precisely regulate their …