Distinct regulatory functions and biological roles of lncRNA splice variants

MR Khan, M Avino, RJ Wellinger, B Laurent - Molecular Therapy-Nucleic …, 2023 - cell.com
Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In
humans, 90%–95% of multi-exon genes produce alternatively spliced RNA transcripts …

Evaluation of long non-coding RNA (LncRNA) in the pathogenesis of chemotherapy resistance in cervical cancer: diagnostic and prognostic approach

N Modabber, SS Mahboub, S Khoshravesh… - Molecular …, 2023 - Springer
Cervical cancer (CC), caused by human papillomavirus (HPV), is a leading cause of female
malignancies worldwide. Therefore, understanding the underlying mechanisms of CC …

Autophagy in combination therapy of temozolomide and IFN-γ in C6-induced glioblastoma: role of non-coding RNAs

H Bashiri, M Moazam-Jazi, MR Karimzadeh… - …, 2023 - Taylor & Francis
Aim: We predicted the modulation of autophagy and apoptosis in response to temozolomide
(TMZ) and IFN-γ based on changes in the expression of non-coding RNAs in C6-induced …

Machine learning-based integration develops an immunogenic cell death-derived lncRNA signature for predicting prognosis and immunotherapy response in lung …

J Sun, H Guo, S Zhang, Y Nie, S Zhou, Y Zeng… - Scientific Reports, 2024 - nature.com
Accumulating evidence demonstrates that lncRNAs are involved in the regulation of the
immune microenvironment and early tumor development. Immunogenic cell death occurs …

Aberrantly expressed long noncoding RNAs as potential prognostic biomarkers in newly diagnosed multiple myeloma: A systemic review and meta‐analysis

J Qin, B Ke, T Liu, C Kong, A Li, H Fu, C Jin - Cancer Medicine, 2023 - Wiley Online Library
Background Numerous studies have manifested long noncoding RNAs (lncRNAs) as
biomarkers to determine the prognosis of multiple myeloma (MM) patients. Nevertheless, the …

Long Noncoding RNA Expression in Acute Lymphoblastic Leukemia: A Systematic Review

SC Lobo-Alves, LA de Oliveira, GC Kretzschmar… - Critical Reviews in …, 2024 - Elsevier
Long noncoding RNAs (lncRNAs), as gene expression modulators, are potential players in
Acute Lymphoblastic Leukemia (ALL) pathogenesis. We systematically explored current …

Comprehensive analysis of the prognostic value and molecular function of CRNDE in glioma at bulk and single-cell levels

L Song, X Li, X Xu, X Huo, Y Zheng, X Wang, D Li… - Cells, 2022 - mdpi.com
Colorectal neoplasia differentially expressed (CRNDE) is an oncogenic long noncoding
RNA (lncRNA) overexpressed in diverse malignancies. Here, we comprehensively analyze …

A comprehensive review of lncRNA CRNDE in cancer progression and pathology, with a specific glance at the epithelial-mesenchymal transition (EMT) process

SA Jasim, SIS Al-Hawary, A Hjazi, I Ahmad… - … -Research and Practice, 2024 - Elsevier
It has been suggested that the long non-coding RNAs (lncRNAs), such as colorectal
neoplasia differentially expressed (CRNDE), may contribute to the formation of human …

[HTML][HTML] Long non-coding RNAs as pathophysiological regulators, therapeutic targets and novel extracellular vesicle biomarkers for the diagnosis of inflammatory …

R Heydari, P Karimi, A Meyfour - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing disease of the gastrointestinal (GI)
system that includes two groups, Crohn's disease (CD) and ulcerative colitis (UC). To cope …

Comprehensive analysis of oxidative stress-related lncRNA signatures in glioma reveals the discrepancy of prognostic and immune infiltration

Z Shi, Y Wu, Q Zhuo, Y Zuo, J Lin, H Shi, H Zhou… - Scientific Reports, 2023 - nature.com
Oxidative stress refers to the process of reactive oxide species (ROS) increase in human
body due to various factors, which leads to oxidative damage in human tissues. Current …