Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine
Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …
tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and …
Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements
J Doorn, G Moll, K Le Blanc… - … Engineering Part B …, 2012 - liebertpub.com
Among the various types of cell-to-cell signaling, paracrine signaling comprises those
signals that are transmitted over short distances between different cell types. In the human …
signals that are transmitted over short distances between different cell types. In the human …
Multipotent stem cell and current application
A Sobhani, N Khanlarkhani, M Baazm… - Acta Medica …, 2017 - acta.tums.ac.ir
Stem cells are self-renewing and undifferentiated cell types that can be differentiate into
functional cells. Stem cells can be classified into two main types based on their source of …
functional cells. Stem cells can be classified into two main types based on their source of …
The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment
DG Leuning, NRM Beijer, NA Du Fossé, S Vermeulen… - Scientific reports, 2018 - nature.com
Mesenchymal stromal cells (MSC) secrete factors that contribute to organ homeostasis and
repair in a tissue specific manner. For instance, kidney perivascular mesenchymal stromal …
repair in a tissue specific manner. For instance, kidney perivascular mesenchymal stromal …
Strategies to optimize adult stem cell therapy for tissue regeneration
S Liu, J Zhou, X Zhang, Y Liu, J Chen, B Hu… - International journal of …, 2016 - mdpi.com
Stem cell therapy aims to replace damaged or aged cells with healthy functioning cells in
congenital defects, tissue injuries, autoimmune disorders, and neurogenic degenerative …
congenital defects, tissue injuries, autoimmune disorders, and neurogenic degenerative …
Therapeutic application of multipotent stem cells
H Mirzaei, A Sahebkar, LS Sichani… - Journal of cellular …, 2018 - Wiley Online Library
Cell therapy is an emerging fields in the treatment of various diseases such as
cardiovascular, pulmonary, hepatic, and neoplastic diseases. Stem cells are an integral tool …
cardiovascular, pulmonary, hepatic, and neoplastic diseases. Stem cells are an integral tool …
Biomimetic tissue‐engineered bone substitutes for maxillofacial and craniofacial repair: The potential of cell sheet technologies
F Kawecki, WP Clafshenkel, M Fortin… - Advanced …, 2018 - Wiley Online Library
Maxillofacial defects are complex lesions stemming from various etiologies: accidental,
congenital, pathological, or surgical. A bone graft may be required when the normal …
congenital, pathological, or surgical. A bone graft may be required when the normal …
Adipose-derived stem cell sheets accelerate bone healing in rat femoral defects
In the present study, we investigated whether both adipose-derived stem cell (ADSC) and
osteogenic-induced ADSC sheets could promote bone healing in a rat distal femoral …
osteogenic-induced ADSC sheets could promote bone healing in a rat distal femoral …
Regulation of angiogenesis and bone regeneration with natural and synthetic small molecules
CE Segar, ME Ogle… - Current pharmaceutical …, 2013 - ingentaconnect.com
Regeneration of bone requires the coordinated processes of angiogenesis and
osteogenesis. These repair mechanisms are closely linked through both direct cell-cell …
osteogenesis. These repair mechanisms are closely linked through both direct cell-cell …
Mapping calcium phosphate activated gene networks as a strategy for targeted osteoinduction of human progenitors
J Eyckmans, SJ Roberts, J Bolander, J Schrooten… - Biomaterials, 2013 - Elsevier
Although calcium phosphate-containing biomaterials are promising scaffolds for bone
regenerative strategies, the osteoinductive capacity of such materials is poorly understood …
regenerative strategies, the osteoinductive capacity of such materials is poorly understood …