Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …

This review of the role of platelets in atherothrombosis illuminates the surprisingly numerous
activities of these tiny, anucleate cells and stresses their participation in the inflammatory …

▪ Abstract Homocysteine is a sulfur amino acid whose metabolism stands at the intersection
of two pathways: remethylation to methionine, which requires folate and vitamin B12 (or …

Studies by various investigators have indicated that elevated levels of plasma homocyst (e)
ine are strongly associated with the occurrence of occlusive vascular diseases. With the …

Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …

Homocysteine is increasingly recognized as a risk factor for coronary artery disease. An
understanding of its metabolism and of the importance of vitamins B6 and B12 and folate as …

High plasma levels of homocysteine are the results of the interplay between congenital and
environmental factors. In the last two decades, a growing amount of interest has focused on …

PATHOGENESIS OF HYPERHOMOCYSTEINEMIA OMOCYSTEINE is a non–protein-
forming, sulfur amino acid whose metabolism is at the intersection of The more severe cases …

This review will first place hyperhomocysteinemia in the context of the other established
amino acid abnormalities characteristic of ESRD. What is known from studies of general and …

Platelets play an important, but often under-recognized role in cardiovascular disease. For
example, the normal response of the platelet can be altered, either by increased pro …