Recent advances in the synthesis and antioxidant activity of low molecular mass organoselenium molecules

JM Anghinoni, PT Birmann, MJ da Rocha, CS Gomes… - Molecules, 2023 - mdpi.com
Selenium is an essential trace element in living organisms, and is present in selenoenzymes
with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) …

Synthesis of new organoselenium-based succinanilic and maleanilic derivatives and in silico studies as possible SARS-CoV-2 main protease inhibitors

S Shaaban, YS Al-Faiyz, GM Alsulaim, M Alaasar… - Inorganics, 2023 - mdpi.com
Herein we report the synthesis of organic selenide-based maleanilic and succinanilic acids
in good yields (up to 95%). Their structural identities were elucidated by spectroscopic …

[PDF][PDF] Selenium-modified chitosan induces HepG2 cell apoptosis and differential protein analysis

SJ Sun, P Deng, CE Peng, HY Ji, LF Mao… - Cancer Management …, 2022 - Taylor & Francis
Introduction Chitosan is the product of the natural polysaccharide chitin removing part of the
acetyl group, and exhibits various physiological and bioactive functions. Selenium …

Novel organoselenium-based N-mealanilic acid and its zinc (II) chelate: Catalytic, anticancer, antimicrobial, antioxidant, and computational assessments

S Shaaban, MSS Adam, NM El-Metwaly - Journal of Molecular Liquids, 2022 - Elsevier
Herein we report the synthesis of two novel Zn (II)-complexes (Zn (LgSe) 2 and Zn (Lg) 2)
starting from 4-((4-(methylselanyl) phenyl) amino)-4-oxobut-2-enoic acid (HLgSe) and 4-oxo …

[HTML][HTML] Selenium-containing compounds: a new hope for innovative treatments in Alzheimer's disease and Parkinson's disease

P Pyka, S Garbo, R Fioravanti, C Jacob, M Hittinger… - Drug Discovery …, 2024 - Elsevier
Neurodegenerative diseases are challenging to cure. To date, no cure has been found for
Alzheimer's disease or Parkinson's disease, and current treatments are able only to slow the …

Selenocyanates and selenotetrazoles derivatives: A detailed experimental and theoretical evaluation as corrosion inhibitors for mild steel in aggressive environment

CM Fernandes, P Cordeiro, V Menezes, V Martins… - Electrochimica …, 2024 - Elsevier
This work presents the selenocyanates ESCA and ESCP and their derivatives
selenotetrazoles ETSP and ETSA, which were synthesized with good to excellent yields …

Synthesis, structural characterization, anticancer, antimicrobial, antioxidant, and computational assessments of Zinc (II), Iron (II), and Copper (II) chelates derived from …

S Shaaban, KT Abdullah, K Shalabi… - Applied …, 2024 - Wiley Online Library
Novel selenated azomethine ligand (MSeOH) and its Zn (II), Fe (II), and Cu (II) chelates were
synthesized. Their chemical structures were confirmed by molar conductivity, thermal …

Nomilin from yuzu seed has in vitro antioxidant activity and downregulates melanogenesis in B16F10 melanoma cells through the PKA/CREB signaling pathway

MH Choi, SH Yang, ND Kim, HJ Shin - Antioxidants, 2022 - mdpi.com
Yuzu (Citrus junos) is a citrus plant native to Asian countries, including Korea, Japan, and
China. Yuzu peel and seed contain abundant vitamin C, citric acid, and polyphenols …

[HTML][HTML] Kinetic study of in vitro release of curcumin from chitosan biopolymer and the evaluation of biological efficacy

S Wijayawardana, C Thambiliyagodage… - Arabian Journal of …, 2024 - Elsevier
Sustained release of curcumin from the polymeric carrier system chitosan, a natural
biopolymer material derived from chitin originated from natural shrimp shell waste, was …

Anticancer, Antimicrobial, and Antioxidant Activities of Organodiselenide-Tethered Methyl Anthranilates

B Al-Abdallah, YS Al-Faiyz, S Shaaban - Biomolecules, 2022 - mdpi.com
Novel methyl anthranilate-based organodiselenide hybrids were synthesized, and their
chemical structures were confirmed by state-of-the-art spectroscopic techniques. Their …