[HTML][HTML] The kynurenine pathway in acute kidney injury and chronic kidney disease
Background: The kynurenine pathway (KP) is the major catabolic pathway for tryptophan
degradation. The KP plays an important role as the sole de novo nicotinamide adenine …
degradation. The KP plays an important role as the sole de novo nicotinamide adenine …
Kynurenine pathway in kidney diseases
I Zakrocka, W Załuska - Pharmacological Reports, 2022 - Springer
Kidney diseases have become one of the most common health care problems. Due to a
growing number of advanced aged patients with concomitant disorders the prevalence of …
growing number of advanced aged patients with concomitant disorders the prevalence of …
Chronic kidney disease: a review of proteomic and metabolomic approaches to membranous glomerulonephritis, focal segmental glomerulosclerosis, and IgA …
A Taherkhani, R Farrokhi Yekta, M Mohseni… - Proteome science, 2019 - Springer
Abstract Chronic Kidney Disease (CKD) is a global health problem annually affecting
millions of people around the world. It is a comprehensive syndrome, and various factors …
millions of people around the world. It is a comprehensive syndrome, and various factors …
How will artificial intelligence and bioinformatics change our understanding of IgA Nephropathy in the next decade?
IgA nephropathy (IgAN) is the most common glomerulonephritis. It is characterized by the
deposition of immune complexes containing immunoglobulin A (IgA) in the kidney's …
deposition of immune complexes containing immunoglobulin A (IgA) in the kidney's …
[HTML][HTML] Predicting and defining steroid resistance in pediatric nephrotic syndrome using plasma metabolomics
JR Gooding, S Agrawal, S McRitchie, Z Acuff… - Kidney international …, 2020 - Elsevier
Introduction Nephrotic syndrome (NS) is a kidney disease that affects both children and
adults. Glucocorticoids have been the primary therapy for> 60 years but are ineffective in …
adults. Glucocorticoids have been the primary therapy for> 60 years but are ineffective in …
Localization of metabolites of human kidney tissue with infrared laser-based selected reaction monitoring mass spectrometry imaging and silver-109 nanoparticle …
J Nizioł, J Sunner, I Beech, K Ossoliński… - Analytical …, 2020 - ACS Publications
Infrared (IR) laser ablation-remote-electrospray ionization (LARESI) platform coupled to a
tandem mass spectrometer (MS/MS) operated in selected reaction monitoring (SRM) or …
tandem mass spectrometer (MS/MS) operated in selected reaction monitoring (SRM) or …
[HTML][HTML] Differential regulation of host immunity, microbiota, and metabolism by planktonic and biofilm cells of Lactiplantibacillus paraplantarum LR-1
L Liu, X Chen, X Yin, Y Yang, L Yuan, H Xiao… - Journal of Functional …, 2023 - Elsevier
Probiotics are receiving significant attention due to their considerable health advantages.
However, research involving the effect of probiotic biofilm and planktonic cells on the health …
However, research involving the effect of probiotic biofilm and planktonic cells on the health …
Functional metabolomics analysis elucidating the metabolic biomarker and key pathway change associated with the chronic glomerulonephritis and revealing action …
W Yu, W Yang, MY Zhao, XL Meng - Frontiers in pharmacology, 2020 - frontiersin.org
Chronic glomerulonephritis (CGN) as the culprit of kidney failure can increase the mortality
of critically ill patients and seriously threatens people's health all over the world. This study …
of critically ill patients and seriously threatens people's health all over the world. This study …
Establishment, validation, and initial application of a sensitive LC-MS/MS assay for quantification of the naturally occurring isomers itaconate, mesaconate, and …
M Winterhoff, F Chen, N Sahini, T Ebensen, M Kuhn… - Metabolites, 2021 - mdpi.com
Itaconate is derived from the tricarboxylic acid (TCA) cycle intermediate cis-aconitate and
links innate immunity and metabolism. Its synthesis is altered in inflammation-related …
links innate immunity and metabolism. Its synthesis is altered in inflammation-related …
Metabolomics study reveals blood biomarkers for early diagnosis of chronic kidney disease and IgA nephropathy: A retrospective cross-sectional study
X Fu, ZX Luo, HH Yin, YN Liu, XG Du, W Cheng… - Clinica Chimica …, 2024 - Elsevier
Background and aims Chronic kidney disease (CKD) causes low quality of life and alarming
morbidity and mortality. The crucial to retard CKD progression is to diagnose early for timely …
morbidity and mortality. The crucial to retard CKD progression is to diagnose early for timely …