The optimal choice of euthanasia method for laboratory rodents depends on a number of
factors, including the scientific goals of the study, the need to minimize animal pain and/or …

The sensation that develops as a long breath hold continues is what this article is about. We
term this sensation of an urge to breathe 'air hunger'. Air hunger, a primal sensation, alerts …

Selecting an appropriate, effective euthanasia agent is controversial. Several recent
publications provide clarity on the use of CO2 in laboratory rats and mice. This review …

In the European Union (EU) millions of laboratory mice are used and killed for experimental
and other scientific purposes each year. Although controversially discussed, the use of …

Rodents are the most widely used species for scientific purposes. A critical pre-requisite of
their use, based on utilitarian ethical reasoning, is the provision of a humane death when …

Background: There has been increased concern about the suitability of CO2 as a method for
euthanasia of laboratory mice and rats, including the potential discomfort, pain or distress …

Simple Summary Carbon dioxide is commonly used for stunning animals prior to killing. It
allows several animals to be killed at once, reduces the need for handling, and is a reliable …

Simple Summary Current recommendations for the use of CO2 as a euthanasia agent for
rats require the use of gradual fill methods in order to render the animal insensible prior to …

Rodent euthanasia using exposure to increasing concentrations of CO2 has come under
scrutiny due to concerns of potential pain during the euthanasia process. Alternatives to …

Several questions have been raised in recent years about the euthanasia of laboratory
rodents. Euthanasia using inhaled agents is considered to be a suitable aesthetic method …