Herpes simplex virus cell entry mechanisms: an update

K Madavaraju, R Koganti, I Volety… - Frontiers in cellular …, 2021 - frontiersin.org
Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating
infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and …

Microvesicles and viral infection

DG Meckes Jr, N Raab-Traub - Journal of virology, 2011 - Am Soc Microbiol
Cells secrete various membrane-enclosed microvesicles from their cell surface (shedding
microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly …

Tegument assembly and secondary envelopment of alphaherpesviruses

DJ Owen, CM Crump, SC Graham - Viruses, 2015 - mdpi.com
Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their
ability to establish lifelong latent infection in neurons. As for all herpesviruses …

Natural products as potential lead compounds to develop new antiviral drugs over the past decade

JH Zhao, YW Wang, J Yang, ZJ Tong, JZ Wu… - European Journal of …, 2023 - Elsevier
Virus infection has been one of the main causes of human death since the ancient times.
Even though more and more antiviral drugs have been approved in clinic, long-term use can …

Plus-and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structures

K Radtke, D Kieneke, A Wolfstein, K Michael… - PLoS …, 2010 - journals.plos.org
Many viruses depend on host microtubule motors to reach their destined intracellular
location. Viral particles of neurotropic alphaherpesviruses such as herpes simplex virus 1 …

Structural analysis of herpes simplex virus by optical super-resolution imaging

RF Laine, A Albecka, S Van De Linde, EJ Rees… - Nature …, 2015 - nature.com
Herpes simplex virus type-1 (HSV-1) is one of the most widespread pathogens among
humans. Although the structure of HSV-1 has been extensively investigated, the precise …

Herpesvirus‐bacteria synergistic interaction in periodontitis

C Chen, P Feng, J Slots - Periodontology 2000, 2020 - Wiley Online Library
The etiopathogenesis of severe periodontitis includes herpesvirus‐bacteria coinfection. This
article evaluates the pathogenicity of herpesviruses (cytomegalovirus and Epstein‐Barr …

Clinical management of herpes simplex virus keratitis

BA Labib, DGI Chigbu - Diagnostics, 2022 - mdpi.com
Herpes simplex virus (HSV) keratitis is one of the leading causes of blindness worldwide.
Additionally, up to 90% of the population in some countries is seropositive for HSV. HSV can …

Promising technologies in the field of helminth vaccines

DJ Perera, M Ndao - Frontiers in immunology, 2021 - frontiersin.org
Helminths contribute a larger global burden of disease than both malaria and tuberculosis.
These eukaryotes have caused human infections since before our earliest recorded history …

Extracellular vesicles and their convergence with viral pathways

T Wurdinger, NTN Gatson, L Balaj, B Kaur… - Advances in …, 2012 - Wiley Online Library
Extracellular vesicles (microvesicles), such as exosomes and shed microvesicles, contain a
variety of molecules including proteins, lipids, and nucleic acids. Microvesicles appear …