ADHD co-morbidities: A review of implication of gene× environment effects with dopamine-related genes

M Kanarik, O Grimm, NR Mota, A Reif… - … & Biobehavioral Reviews, 2022 - Elsevier
ADHD is a major burden in adulthood, where co-morbid conditions such as depression,
substance use disorder and obesity often dominate the clinical picture. ADHD has …

Abnormal reward functioning across substance use disorders and major depressive disorder: Considering reward as a transdiagnostic mechanism

AR Baskin-Sommers, D Foti - International Journal of Psychophysiology, 2015 - Elsevier
A common criticism of the Diagnostic and Statistical Manual of Mental Disorders (American
Psychiatric Association, 2013) is that its criteria are based more on behavioral descriptions …

Liking, wanting, and the incentive-sensitization theory of addiction.

KC Berridge, TE Robinson - American Psychologist, 2016 - psycnet.apa.org
Rewards are both “liked” and “wanted,” and those 2 words seem almost interchangeable.
However, the brain circuitry that mediates the psychological process of “wanting” a particular …

Toward biomarkers of the addicted human brain: Using neuroimaging to predict relapse and sustained abstinence in substance use disorder

SJ Moeller, MP Paulus - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
The ability to predict relapse is a major goal of drug addiction research. Clinical and
diagnostic measures are useful in this regard, but these measures do not fully and …

Late positive potential as a candidate biomarker of motivational relevance in substance use: Evidence from a meta-analysis

HE Webber, C de Dios, DA Kessler, JM Schmitz… - Neuroscience & …, 2022 - Elsevier
The objective of the current meta-analysis was to assess the effect size of the Late Positive
Potential (LPP) to drug and emotional cues in substance users compared to controls. The …

Impaired neural response to negative prediction errors in cocaine addiction

MA Parvaz, AB Konova, GH Proudfit… - Journal of …, 2015 - Soc Neuroscience
Learning can be guided by unexpected success or failure, signaled via dopaminergic
positive reward prediction error (+ RPE) and negative reward-prediction error (− RPE) …

[HTML][HTML] Reward Deficiency Syndrome (RDS): a cytoarchitectural common neurobiological trait of all addictions

K Blum, A Bowirrat, ER Braverman, D Baron… - International Journal of …, 2021 - mdpi.com
Alcohol and other substance use disorders share comorbidity with other RDS disorders, ie, a
reduction in dopamine signaling within the reward pathway. RDS is a term that connects …

[HTML][HTML] A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus

H Ekhtiari, M Zare-Bidoky, A Sangchooli, AC Janes… - Nature protocols, 2022 - nature.com
Cue reactivity is one of the most frequently used paradigms in functional magnetic
resonance imaging (fMRI) studies of substance use disorders (SUDs). Although there have …

Neuropsychoimaging measures as alternatives to drug use outcomes in clinical trials for addiction

RZ Goldstein - JAMA psychiatry, 2022 - jamanetwork.com
Cognitive impairments in people with substance use disorders have been reliably
documented, generalizable across multiple domains and substance types. 1 Specific …

[PDF][PDF] Genetic addiction risk score (GARS)™, a predictor of vulnerability to opioid dependence

K Blum, ALC Chen, PK Thanos, M Febo… - Front Biosci (Elite …, 2018 - academia.edu
175 1. ABSTRACT Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid
dependence Kenneth Blum1-8,10,18 Page 1 175 1. ABSTRACT The interaction of …