It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …

The development of new materials based on hydroxyapatite has undergone a great
evolution in recent decades due to technological advances and development of …

Fibrinogen is a key component of the inflammation and clotting pathways and an
established risk factor for cardiovascular disease. Flavonoids have been shown to be …

Fibrinogen has been known since the mid-nineteenth century. Although initially its interest
had been within the field of physiology over time its study has spread to new disciplines …

Herein, we present an integrated computational and experimental study to tackle the
interactions between recognized β-lactam antibiotics (cloxacillin and dicloxacillin) with the …

Raman spectroscopy is used in the study of the tertiary structure of proteins. The effect of
cleavage of disulfide bonds (using DTT and TCEP agents) on the molecular structure and …

Variable-temperature (VT) Fourier transform infrared (FTIR) spectroscopy was employed to
examine changes in secondary structure of whole plasma proteins as well as of plasma …

Protein aggregation plays important roles in life science as, for instance, those associated to
neurodegenerative diseases. Although extensive efforts have been done to elucidate all the …

In this work we present a computational analysis together with experimental studies,
focusing on the interaction between a benzothiazole (BTS) and lysozyme. Results obtained …

In this study we present an in-depth and detailed analysis of the binding process between
two antibiotics (cloxacillin and dicloxacillin) and a blood serum protein (lysozyme). Our …