Nanoparticles-mediated ion channels manipulation: From their membrane interactions to bioapplications

Q Huang, W Zhu, X Gao, X Liu, Z Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Ion channels are transmembrane proteins ubiquitously expressed in all cells that control
various ions (eg Na+, K+, Ca 2+ and Cl-etc) crossing cellular plasma membrane, which play …

Small-molecule fluorescent probes: big future for specific bacterial labeling and infection detection

Z Wang, B Xing - Chemical Communications, 2022 - pubs.rsc.org
Bacterial infections remain a global healthcare problem that is particularly attributed to the
spread of antibiotic resistance and the evolving pathogenicity. Accurate and swift …

Killing three birds with one stone: Near-infrared light triggered nitric oxide release for enhanced photodynamic and anti-inflammatory therapy in refractory keratitis

H Zhang, W Jiang, Y Peng, J Yang, X Chu, Z Long, R Li… - Biomaterials, 2022 - Elsevier
Stubborn resistant bacteria, bacterial biofilms and severe inflammation are challenging
issues in refractory keratitis treatment. Herein, we design a multifunctional near-infrared light …

A single-atom Cu–N 2 catalyst eliminates oxygen interference for electrochemical sensing of hydrogen peroxide in a living animal brain

X Gao, W Ma, J Mao, CT He, W Ji, Z Chen, W Chen… - Chemical …, 2021 - pubs.rsc.org
Hydrogen peroxide (H2O2) plays essential roles in various physiological and pathological
processes. The electrochemical hydrogen peroxide reduction reaction (HPRR) has been …

Enzyme-activated near-infrared fluorogenic probe with high-efficiency intrahepatic targeting ability for visualization of drug-induced liver injury

Y Zhang, X Chen, Q Yuan, Y Bian, M Li, Y Wang… - Chemical …, 2021 - pubs.rsc.org
Hepatotoxicity is a serious problem faced by thousands of clinical drugs, and drug-induced
liver injury (DILI) caused by chronic administration or overdose has become a major …

Red emissive two-photon carbon dots: photodynamic therapy in combination with real-time dynamic monitoring for the nucleolus

S Yi, S Deng, X Guo, C Pang, J Zeng, S Ji, H Liang… - Carbon, 2021 - Elsevier
Abstract Treatment in combination with real-time monitoring of dynamic organelle changes
is of great significance for evaluating therapeutic efficacy. However, it remains highly …

Cyanine‐dyad molecular probe for the simultaneous profiling of the evolution of multiple radical species during bacterial infections

Z Wang, TD Cong, W Zhong, JW Lau… - Angewandte Chemie …, 2021 - Wiley Online Library
Real‐time monitoring of the evolution of bacterial infection‐associated multiple radical
species is critical to accurately profile the pathogenesis and host‐defense mechanisms …

Lanthanide-doped inorganic nanoprobes for luminescent assays of biomarkers

L Wang, S Han, C Li, D Tu, X Chen - Accounts of Materials …, 2023 - ACS Publications
Conspectus Tremendous progress in nanomaterial and nanotechnology has been made in
recent years, which greatly contributes to the development of inorganic nanoparticles (NPs) …

Near‐infrared light‐triggered polyprodrug/siRNA loaded upconversion nanoparticles for multi‐modality imaging and synergistic cancer therapy

G Kuang, H Lu, S He, H Xiong, J Yu… - Advanced …, 2021 - Wiley Online Library
Stimuli‐responsive nanosystems have been widely applied as effective modalities for
drug/gene co‐delivery in cancer treatment. However, precise spatiotemporal manipulations …

Fluorescent probes for in vitro and in vivo quantification of hydrogen peroxide

S Ye, JJ Hu, QA Zhao, D Yang - Chemical Science, 2020 - pubs.rsc.org
Hydrogen peroxide (H2O2) plays essential roles in redox signaling and oxidative stress, and
its dynamic concentration is critical to human health and diseases. Here we report the …