Mechanical stimulation to stimulate formation of a physiological collagen architecture in tissue-engineered cartilage: a numerical study

M Khoshgoftar, CC van Donkelaar… - Computer methods in …, 2011 - Taylor & Francis
The load-bearing capacity of today's tissue-engineered (TE) cartilage is insufficient. The
arcade-like collagen network in native cartilage plays an important role in its load-bearing …

Approach to Design Loading Protocols for Cartilage Tissue Engineering: Hypothesis, Experiment and Model

CC Van Donkelaar… - Summer …, 2010 - asmedigitalcollection.asme.org
Tissue engineered cartilage has reached the level of maturity where the cells, either
chondrocytes, BMSC's or other cells are stimulated to produce a tissue of which the …

[PDF][PDF] Optimization of Sliding Indentation Loading to Induce Physiological Collagen Architecture in Growing Tissue Engineered Cartilage

M Khoshgoftar, CC van Donkelaar, LM Kock… - Proceedings of the …, 2010 - termis.org
Currently, the load-bearing capacity of tissueengineered cartilage is insufficient. Inducing
sufficient collagen content with an arcade-like architecture is a solution. Recently, sliding …