[HTML][HTML] Recent developments in the isolation, biological function, biosynthesis, and synthesis of phenazine natural products
N Guttenberger, W Blankenfeldt… - Bioorganic & medicinal …, 2017 - Elsevier
Phenazines are natural products which are produced by bacteria or by archaeal
Methanosarcina species. The tricyclic ring system enables redox processes, which …
Methanosarcina species. The tricyclic ring system enables redox processes, which …
[HTML][HTML] Recent advances in malaria drug discovery
MA Biamonte, J Wanner, KG Le Roch - Bioorganic & medicinal chemistry …, 2013 - Elsevier
This digest covers some of the most relevant progress in malaria drug discovery published
between 2010 and 2012. There is an urgent need to develop new antimalarial drugs. Such …
between 2010 and 2012. There is an urgent need to develop new antimalarial drugs. Such …
Regio‐and enantioselective photodimerization within the confined space of a homochiral ruthenium/palladium heterometallic coordination cage
J Guo, YW Xu, K Li, LM Xiao, S Chen, K Wu… - Angewandte …, 2017 - Wiley Online Library
The photoinduced regio‐and enantioselective coupling of naphthols and derivatives thereof
is achieved in the confined chiral coordination space of a RuII metalloligand based cage …
is achieved in the confined chiral coordination space of a RuII metalloligand based cage …
Current scenario of artemisinin and its analogues for antimalarial activity
Human malaria, one of the most striking, reemerging infectious diseases, is caused by
several types of Plasmodium parasites. Whilst advances have been made in lowering the …
several types of Plasmodium parasites. Whilst advances have been made in lowering the …
Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones
EN da Silva Júnior, GAM Jardim, C Jacob… - European Journal of …, 2019 - Elsevier
Naphthoquinones are of key importance in organic synthesis and medicinal chemistry. In the
last few years, various synthetic routes have been developed to prepare bioactive …
last few years, various synthetic routes have been developed to prepare bioactive …
Sulfur‐Catalyzed Oxidative Condensation of Aryl Alkyl Ketones with o‐Phenylenediamines: Access to Quinoxalines
LA Nguyen, TTT Nguyen, QA Ngo… - Advanced Synthesis & …, 2022 - Wiley Online Library
While elemental sulfur has been largely used as oxidant or sulfurating agent, its role as a
catalyst has not been developed. We report here its catalytic activity in the oxidative …
catalyst has not been developed. We report here its catalytic activity in the oxidative …
Synthesis of quinoidal molecules: strategies towards bioactive compounds with an emphasis on lapachones
SL de Castro, FS Emery, EN da Silva Junior - European journal of …, 2013 - Elsevier
Naphthoquinoidal compounds are of great interest in medicinal chemistry. In recent years,
several synthetic routes have been developed to obtain bioactive molecules derived from …
several synthetic routes have been developed to obtain bioactive molecules derived from …
An overview on the antimalarial activity of 1, 2, 4‐trioxanes, 1, 2, 4‐trioxolanes and 1, 2, 4, 5‐tetraoxanes
M Shukla, K Rathi, M Hassam… - Medicinal Research …, 2024 - Wiley Online Library
The demand for novel, fast‐acting, and effective antimalarial medications is increasing
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …
Dual drug loaded PLGA nanospheres for synergistic efficacy in breast cancer therapy
MS Deepika, R Thangam, TS Sheena… - Materials Science and …, 2019 - Elsevier
Improved therapeutic effects can be achieved by the delivery of combination of drugs
through multifunctional cell targeted nanocarrier systems. The present investigation reports …
through multifunctional cell targeted nanocarrier systems. The present investigation reports …
Artemisinin‐derived antimalarial endoperoxides from bench‐side to bed‐side: chronological advancements and future challenges
MK Tiwari, S Chaudhary - Medicinal Research Reviews, 2020 - Wiley Online Library
Abstract According to WHO World Malaria Report (2018), nearly 219 million new cases of
malaria occurred and a total no. of 435 000 people died in 2017 due to this infectious …
malaria occurred and a total no. of 435 000 people died in 2017 due to this infectious …