Astragali Radix (Huangqi): A promising edible immunomodulatory herbal medicine

Z Chen, L Liu, C Gao, W Chen, CT Vong, P Yao… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Astragali Radix (AR, Huangqi in Chinese), the
dried root of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or A …

Immunomodulatory properties of triterpenes

G Renda, İ Gökkaya, D Şöhretoğlu - Phytochemistry Reviews, 2022 - Springer
The immune system is one of the main defence mechanisms of the human body.
Inadequacy of this system or immunodeficiency results in increased risk of infections and …

Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus

L Wang, Z Jiang, J Zhang, K Chen, M Zhang… - Nature …, 2023 - nature.com
Acetylation contributes to the bioactivity of numerous medicinally important natural products.
However, little is known about the acetylation on sugar moieties. Here we report a saponin …

Anti-inflammatory and immunostimulatory activities of astragalosides

Y Qi, F Gao, L Hou, C Wan - The American Journal of Chinese …, 2017 - World Scientific
Astragalus membranaceus (Fisch) Bge (Huang-Qi) is a well-known herbal medicine with
tonic property and has been widely used to treat cancer and other immune disorders in …

Absorption, disposition, and pharmacokinetics of saponins from Chinese medicinal herbs: what do we know and what do we need to know more?

K Yu, F Chen, C Li - Current drug metabolism, 2012 - ingentaconnect.com
Saponins are a group of amphiphilic glycosides containing one or more sugar chains linked
to a nonpolar triterpene or steroid aglycone skeleton, which are believed to be responsible …

Biological active ingredients of traditional Chinese herb Astragalus membranaceus on treatment of diabetes: a systematic review

Z Kai, P Michela, P Antonio… - Mini reviews in …, 2015 - ingentaconnect.com
Diabetes mellitus (DM) is a serious chronic metabolic disease which disease afflicting at
present now afflicts approximately 4% of world population worldwide. Nowadays, the need …

Evaluation of the immunomodulatory properties in mice and in vitro anti-inflammatory activity of cycloartane type saponins from Astragalus species

A Nalbantsoy, T Nesil, Ö Yılmaz-Dilsiz, G Aksu… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Astragalus roots are used to treat leukemia
and for their wound healing properties in Southeast Anatolia-Turkey. MATERIALS AND …

Recent progress in phytochemistry, pharmacology and biotechnology of Astragalus saponins

I Ionkova, A Shkondrov, I Krasteva, T Ionkov - Phytochemistry reviews, 2014 - Springer
Saponins are widely distributed among plant kingdom and possess a wide range of
pharmacological properties. Genus Astragalus is the largest in the Fabaceae family …

[HTML][HTML] Total phenolic, flavonoid contents, and biological activities of stem extracts of Astragalus spinosus (Forssk.) Muschl. grown in Northern Border Province, Saudi …

N Nayeem, M Imran, SMB Asdaq, SI Rabbani… - Saudi Journal of …, 2022 - Elsevier
Abstract Background and objective Genus Astragalus belongs to the family Fabaceae and is
one among the largest genera consisting of around 3000 species. The plants have been …

Immunomodulatory, hemolytic and cytotoxic activity potentials of triterpenoid saponins from eight Cephalaria species

NB Sarikahya, A Nalbantsoy, H Top, RS Gokturk… - Phytomedicine, 2018 - Elsevier
Background Saponins isolated from a number of plants possess a broad spectrum of
biological and pharmacological activities by using in vitro and in vivo bioassays. The recent …