The genetic background of Brazilians encompasses Amerindian, African, and European
components as a result of the colonization of an already Amerindian inhabited region by …

Inflammation impairs renal allograft survival but is difficult to quantify by eye at low densities.
Here we measured leukocyte abundance in early surveillance biopsies by digital image …

The modulation of the immune system following solid organ transplantation has made
considerable progress with new immunosuppressive regimens and has considerably …

Evidence showed that chemokines serve as pro-migratory factors for immune cells. CCL3,
CCL4 and CCL5, as the main CC chemokines subfamily members, activate immune cells …

Background Production of reactive oxygen species (ROS) and thereby induction of oxidative
stress seem to be one of the major mediators of inflammatory adverse outcomes after renal …

Materials and Methods. The IL10-1082G> A and TNF-308G> A polymorphisms were
determined in 100 kidney allograft recipients and their donors using the polymerase chain …

Background Acute rejection (AR) after renal transplantation affects both patient and graft
survival. There is growing evidence of the genetic association between cytokine or its …

Delayed graft function (DGF) is defined as the need for dialysis within 7 days following
kidney transplantation (KTx). DGF is associated with increased costs, higher risk for acute …

Materials and Methods. One hundred and eighty-two donorrecipient pairs were studied.
Lipid peroxidation and total antioxidant capacity were measured in the recipients' plasma as …

Background: Angiotensin converting enzyme (ACE) is involved in various
pathophysiological conditions including renal function. ACE levels are under genetic control …