d-Amino acids: new clinical pathways for brain diseases
IN de Oliveira Souza, R Roychaudhuri… - Trends in Molecular …, 2023 - cell.com
Free d-amino acids (d-AAs) are emerging as a novel and important class of signaling
molecules in many organs, including the brain and endocrine systems. There has been …
molecules in many organs, including the brain and endocrine systems. There has been …
Rational and translational implications of D-amino acids for treatment-resistant schizophrenia: from neurobiology to the clinics
A de Bartolomeis, L Vellucci, MC Austin, G De Simone… - Biomolecules, 2022 - mdpi.com
Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …
Co-exposure of butyl benzyl phthalate and TiO2 nanomaterials (anatase) in Metaphire guillelmi: Gut health implications by transcriptomics
X Yang, J Xu, X Chen, M Yao, M Pei, Y Yang… - Journal of …, 2024 - Elsevier
During the COVID-19 pandemic, an abundance of plastic face masks has been consumed
and disposed of in the environment. In addition, substantial amounts of plastic mulch film …
and disposed of in the environment. In addition, substantial amounts of plastic mulch film …
Dysfunctional peroxisomal lipid metabolisms and their ocular manifestations
Retina is rich in lipids and dyslipidemia causes retinal dysfunction and eye diseases. In
retina, lipids are not only important membrane component in cells and organelles but also …
retina, lipids are not only important membrane component in cells and organelles but also …
Discover boy specific-biomarkers and reveal gender-related metabolic differences in central precocious puberty
J Wu, L Wen, J Chen, Y Chang, R Huang, Y Lin… - The Journal of Steroid …, 2023 - Elsevier
The incidence of central precocious puberty (CPP) in boys is rising, but lack of effective
molecular biomarkers often leads to delayed treatment and thus the terrible clinical …
molecular biomarkers often leads to delayed treatment and thus the terrible clinical …
On the regulation of human D‐aspartate oxidase
V Rabattoni, Z Motta, M Miceli, G Molla… - Protein …, 2023 - Wiley Online Library
The human flavoenzyme D‐aspartate oxidase (hDASPO) controls the level of D‐aspartate in
the brain, a molecule acting as an agonist of NMDA receptors and modulator of AMPA and …
the brain, a molecule acting as an agonist of NMDA receptors and modulator of AMPA and …
Chiral amino acid profiling in serum reveals potential biomarkers for Alzheimer's disease
M Liu, M Li, J He, Y He, J Yang… - Journal of Alzheimer's …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) is a complex neurodegenerative disease, and
increasing evidence has linked dysregulation of amino acids to AD pathogenesis. However …
increasing evidence has linked dysregulation of amino acids to AD pathogenesis. However …
Amino Acid Chirality: Stereospecific Conversion and Physiological Implications
K Das, H Balaram, K Sanyal - ACS omega, 2024 - ACS Publications
The absolute configuration dictates the biological role of chiral molecules in the living world.
This is best exemplified by all ribosomally synthesized polypeptides having chiral amino …
This is best exemplified by all ribosomally synthesized polypeptides having chiral amino …
Decreased free D-aspartate levels in the blood serum of patients with schizophrenia
M Garofalo, G De Simone, Z Motta, T Nuzzo… - Frontiers in …, 2024 - frontiersin.org
Introduction Schizophrenia (SCZ) and autism spectrum disorder (ASD) are
neurodevelopmental diseases characterized by different psychopathological manifestations …
neurodevelopmental diseases characterized by different psychopathological manifestations …
Genetic variants in DDO and PEX5L in peroxisome‐related pathways predict non‐small cell lung cancer survival
Peroxisomes play a role in lipid metabolism and regulation of reactive oxygen species, but
its role in development and progression of non‐small cell lung cancer (NSCLC) is not well …
its role in development and progression of non‐small cell lung cancer (NSCLC) is not well …