Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

Global geographic trends in antimicrobial resistance: the role of international travel

I Frost, TP Van Boeckel, J Pires, J Craig… - Journal of travel …, 2019 - academic.oup.com
Background Rising antimicrobial resistance (AMR) is a threat to modern medicine, and
increasing international mobility facilitates the spread of AMR. Infections with resistant …

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

RS Hendriksen, P Munk, P Njage, B Van Bunnik… - Nature …, 2019 - nature.com
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining
representative data on AMR for healthy human populations is difficult. Here, we use …

Multidrug evolutionary strategies to reverse antibiotic resistance

M Baym, LK Stone, R Kishony - Science, 2016 - science.org
BACKGROUND Antibiotics are among the most important tools in medicine, but their efficacy
is threatened by the evolution of resistance. Since the earliest days of antibiotics, resistance …

Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

JK Vogt, M Kristensen, LBS Hansen, S Ibrügger… - Gut, 2019 - gut.bmj.com
Objective To investigate whether a whole grain diet alters the gut microbiome and insulin
sensitivity, as well as biomarkers of metabolic health and gut functionality. Design 60 Danish …

The structure and diversity of human, animal and environmental resistomes

C Pal, J Bengtsson-Palme, E Kristiansson… - Microbiome, 2016 - Springer
Abstract Background Antibiotic resistance genes (ARGs) are widespread but cause
problems only when present in pathogens. Environments where selection and transmission …

Wastewater surveillance of antibiotic-resistant bacterial pathogens: A systematic review

A Tiwari, P Kurittu, AI Al-Mustapha, V Heljanko… - Frontiers in …, 2022 - frontiersin.org
Infectious diseases caused by antibiotic-resistant bacterial (ARB) pathogens are a serious
threat to human and animal health. The active surveillance of ARB using an integrated one …

Abundance and diversity of the faecal resistome in slaughter pigs and broilers in nine European countries

P Munk, BE Knudsen, O Lukjancenko, ASR Duarte… - Nature …, 2018 - nature.com
Antimicrobial resistance (AMR) in bacteria and associated human morbidity and mortality is
increasing. The use of antimicrobials in livestock selects for AMR that can subsequently be …

Molecular surveillance of norovirus, 2005–16: an epidemiological analysis of data collected from the NoroNet network

J van Beek, M de Graaf, H Al-Hello, DJ Allen… - The Lancet Infectious …, 2018 - thelancet.com
Background The development of a vaccine for norovirus requires a detailed understanding
of global genetic diversity of noroviruses. We analysed their epidemiology and diversity …

Complexities in understanding antimicrobial resistance across domesticated animal, human, and environmental systems

DW Graham, G Bergeron, MW Bourassa… - Annals of the New …, 2019 - Wiley Online Library
Antimicrobial resistance (AMR) is a significant threat to both human and animal health. The
spread of AMR bacteria and genes across systems can occur through a myriad of pathways …