Cellular transplantation is emerging as a potential mechanism with which to augment
myocyte number in diseased hearts. To date a number of cell types have been shown to …

Myocardial regeneration can be induced with the implantation of a variety of myogenic and
angiogenic cell types. More than 150 patients have been treated with cellular …

Objective: The effect of transplanted mesenchymal stem cells (MSCs) on the left ventricular
(LV) function and morphology in a rat myocardial infarct heart with reperfusion model were …

BACKGROUND: Recent evidences have suggested that stem cell can differentiate into
cardiomyocyte and smooth muscle cell (SMC) in vivo or in vitro. But the mechanism on how …

Background—Bone marrow stromal cells (BMSCs) have the potential to differentiate into
various cells and can transdifferentiate into myocytes if an appropriate cellular environment …

Background: Current clinical experience with cellular cardiomyoplasty (using serum bovine-
cultivated myoblasts) has demonstrated significant malignant ventricular arrhythmias and …

Regenerating new tissue using cell transplantation has relied on successful cell engraftment
in the host; however, cell engraftment into the diabetic skin wound is not as successful as in …

Background Bone marrow stem cell clonal dysfunction by somatic mutation is suspected to
affect post-infarction myocardial regeneration after coronary bypass surgery (CABG) …

The incidence of heart failure is achieving epidemic proportions. Adult human myocytes
cannot regenerate because these cells do not reenter the cell cycle. In patients with heart …

Bone marrow stroma contains a subgroup of cells which can be guided in vitro to
differentiate, and express cardiomyocyte phenotype. In vivo, these cells can become …