Ruminococcus gnavus: friend or foe for human health

EH Crost, E Coletto, A Bell… - FEMS Microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Blautia—a new functional genus with potential probiotic properties?

X Liu, B Mao, J Gu, J Wu, S Cui, G Wang, J Zhao… - Gut …, 2021 - Taylor & Francis
Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the
feces and intestines of mammals. Based on phenotypic and phylogenetic analyses, some …

Advancing human gut microbiota research by considering gut transit time

N Procházková, G Falony, LO Dragsted, TR Licht… - Gut, 2023 - gut.bmj.com
Accumulating evidence indicates that gut transit time is a key factor in shaping the gut
microbiota composition and activity, which are linked to human health. Both population-wide …

Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

K Oliphant, E Allen-Vercoe - Microbiome, 2019 - Springer
The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

Performance and application of 16S rRNA gene cycle sequencing for routine identification of bacteria in the clinical microbiology laboratory

DL Church, L Cerutti, A Gürtler, T Griener… - Clinical microbiology …, 2020 - Am Soc Microbiol
This review provides a state-of-the-art description of the performance of Sanger cycle
sequencing of the 16S rRNA gene for routine identification of bacteria in the clinical …

Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol

M Yang, X Qi, N Li, JT Kaifi, S Chen, AA Wheeler… - Nature …, 2023 - nature.com
The interplay between western diet and gut microbiota drives the development of non-
alcoholic fatty liver disease and its progression to non-alcoholic steatohepatitis. However …

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients

AB Hall, M Yassour, J Sauk, A Garner, X Jiang… - Genome medicine, 2017 - Springer
Background Inflammatory bowel disease (IBD) is characterized by chronic inflammation of
the gastrointestinal tract that is associated with changes in the gut microbiome. Here, we …

Functional and genomic variation between human-derived isolates of Lachnospiraceae reveals inter-and intra-species diversity

MT Sorbara, ER Littmann, E Fontana, TU Moody… - Cell host & …, 2020 - cell.com
Bacteria belonging to the Lachnospiraceae family are abundant, obligate anaerobic
members of the microbiota in healthy humans. Lachnospiraceae impact their hosts by …

Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal

D Azzouz, A Omarbekova, A Heguy… - Annals of the …, 2019 - ard.bmj.com
Background/Purpose To search for a transmissible agent involved in lupus pathogenesis,
we investigated the faecal microbiota of patients with systemic lupus erythematosus (SLE) …

Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease

K Nishino, A Nishida, R Inoue, Y Kawada… - Journal of …, 2018 - Springer
Background The mucosa-associated gut microbiota directly modulates epithelial and
mucosal function. In this study, we investigated the mucosa-associated microbial community …