[HTML][HTML] Programmed cell death in diabetic nephropathy: a review of apoptosis, autophagy, and necroptosis

NS Erekat - Medical Science Monitor: International Medical Journal …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …

[HTML][HTML] Programmed cell death in cerebellar Purkinje neurons

NS Erekat - Journal of integrative neuroscience, 2022 - imrpress.com
Apoptosis, autophagy and necrosis are the three main types of programmed cell death. One
or more of these types of programmed cell death may take place in neurons leading to their …

[HTML][HTML] Role of endometrial autophagy in physiological and pathophysiological processes

S Yang, H Wang, D Li, M Li - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Endometrium is the mucosal lining of the uterus which expressed a cyclic process of
proliferation, secretion and scaling under the control of hormones secreted by the ovary, and …

[HTML][HTML] Autophagy and its association with genetic mutations in parkinson disease

NS Erekat - Medical science monitor: international medical journal …, 2022 - ncbi.nlm.nih.gov
Parkinson disease is the second most common neurodegenerative disorder, affecting 0.1–
0.2% of the general population. It is a progressive debilitating disorder caused by …

[HTML][HTML] Paeonol alleviates migration and invasion of endometrial stromal cells by reducing HIF-1α-regulated autophagy in endometriosis

C Pang, Z Wu, X Xu, W Yang, X Wang… - Frontiers in Bioscience …, 2021 - imrpress.com
Background: Dysregulated migration and invasion of endometrial stromal cells is implicated
in the pathogenesis of endometriosis. Hypoxia functions as critical microenvironmental …

[HTML][HTML] Interleukin-1 beta and tumor necrosis factor alpha upregulation and nuclear factor kappa B activation in skeletal muscle from a mouse model of chronic …

NS Erekat, MD Al-Jarrah - Medical science monitor: international …, 2018 - ncbi.nlm.nih.gov
Background Skeletal muscle atrophy has been reported in patients with Parkinson disease
(PD). The purpose of this study was to examine the potential implication of interleukin 1 beta …

[HTML][HTML] Association of Parkinson disease induction with cardiac upregulation of apoptotic mediators P53 and active caspase-3: An immunohistochemistry study

NS Erekat, MD Al-Jarrah - Medical science monitor basic research, 2018 - ncbi.nlm.nih.gov
Background Apoptosis plays a key role in the pathogenesis of Parkinson disease (PD).
Active caspase-3, which is a proapoptotic factor, has been shown to reduce cardiac …

Active caspase-3 upregulation is augmented in at-risk cerebellar Purkinje cells following inferior olive chemoablation in the shaker mutant rat: an immunofluorescence …

NS Erekat - Neurological research, 2019 - Taylor & Francis
ABSTRACT Objectives: Mechanisms underlying Purkinje cell (PC) death, which leads to
many diseases in humans, are still poorly elucidated. Progressive PC degeneration occurs …

Treadmill exercise training could attenuate the upregulation of interleukin-1 beta and tumor necrosis factor alpha in the skeletal muscle of mouse model of chronic …

MD Al-Jarrah, NS Erekat - NeuroRehabilitation, 2018 - content.iospress.com
BACKGROUND: Induction of Parkinson disease (PD) causes interleukin-1 beta (IL-1β) and
tumor necrosis factor-alpha (TNF-α) upregulation in gastrocnemius skeletal muscles …

Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat

KP Figueroa, CJ Anderson, S Paul… - Human Molecular …, 2023 - academic.oup.com
The shaker rat carries a naturally occurring mutation leading to progressive ataxia
characterized by Purkinje cell (PC) loss. We previously reported on fine-mapping the shaker …