Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Carbon monoxide and its controlled release: therapeutic application, detection, and development of carbon monoxide releasing molecules (CORMs) miniperspective

K Ling, F Men, WC Wang, YQ Zhou… - Journal of Medicinal …, 2017 - ACS Publications
Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

Carbon monoxide–physiology, detection and controlled release

SH Heinemann, T Hoshi, M Westerhausen… - Chemical …, 2014 - pubs.rsc.org
Carbon monoxide (CO) is increasingly recognized as a cell-signalling molecule akin to nitric
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …

Recent development of luminescent rhenium (I) tricarbonyl polypyridine complexes as cellular imaging reagents, anticancer drugs, and antibacterial agents

LCC Lee, KK Leung, KKW Lo - Dalton Transactions, 2017 - pubs.rsc.org
There has been fast-growing interest in the exploitation of the photophysical and
photochemical properties of luminescent transition metal complexes in biological …

Novel lead structures and activation mechanisms for CO‐releasing molecules (CORMs)

U Schatzschneider - British journal of pharmacology, 2015 - Wiley Online Library
Carbon monoxide (CO) is an endogenous small signalling molecule in the human body,
produced by the action of haem oxygenase on haem. Since it is very difficult to apply safely …

[图书][B] Metals in medicine

JC Dabrowiak - 2017 - books.google.com
Working from basic chemical principles, Metals in Medicine, 2nd Edition describes a wide
range of metal-based agents for treating and diagnosing disease. Thoroughly revised and …

Design strategies to improve the sensitivity of photoactive metal carbonyl complexes (photoCORMs) to visible light and their potential as CO-donors to biological …

I Chakraborty, SJ Carrington… - Accounts of Chemical …, 2014 - ACS Publications
Conspectus The recent surprising discovery of the beneficial effects of carbon monoxide
(CO) in mammalian physiology has drawn attention toward site-specific delivery of CO to …

Metal coordination complexes as therapeutic agents for ischemia-reperfusion injury

NP Bigham, JJ Wilson - Journal of the American Chemical Society, 2023 - ACS Publications
Ischemia-reperfusion injury (IRI), which describes the cell damage and death that occurs
after blood and oxygen are restored to ischemic or hypoxic tissue, is a significant factor …