Surface modification of lipid-based nanoparticles

Y Xu, T Fourniols, Y Labrak, V Préat, A Beloqui… - ACS …, 2022 - ACS Publications
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

[HTML][HTML] A review on the latest developments of mesoporous silica nanoparticles as a promising platform for diagnosis and treatment of cancer

F Ahmadi, A Sodagar-Taleghani… - International Journal of …, 2022 - Elsevier
Cancer is the second cause of human mortality after cardiovascular disease around the
globe. Conventional cancer therapies are chemotherapy, radiation, and surgery. In fact, due …

[HTML][HTML] Surface design of nanocarriers: Key to more efficient oral drug delivery systems

H Spleis, M Sandmeier, V Claus… - Advances in colloid and …, 2023 - Elsevier
As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Alkaline phosphatase: a reliable endogenous partner for drug delivery and diagnostics

B Le‐Vinh, ZB Akkuş‐Dağdeviren… - Advanced …, 2022 - Wiley Online Library
Since the 1960s the membrane‐bound enzyme alkaline phosphatase (ALP) has been
utilized in drug delivery. As it cleaves phosphate substructures from drugs, auxiliary agents …

Pteroyl-γ-l-glutamate/Pluronic® F68 modified polymeric micelles loaded with docetaxel for targeted delivery and reduced toxicity

N Rarokar, R Agrawal, S Yadav, P Khedekar… - Journal of Molecular …, 2023 - Elsevier
Targeting the cancerous cells is essential to improve the drug's efficacy and avoid toxicity to
normal cells, which can be achieved by surface functionalizing the nanocarriers like …

Nanoemulsion in management of colorectal cancer: challenges and future prospects

P Mohite, T Rajput, R Pandhare, A Sangale, S Singh… - …, 2023 - mdpi.com
The second most significant cause of cancer-related mortality and morbidity in the United
States is colorectal cancer (CRC), the third most diagnosed malignancy. People over 50 …

Drug permeation enhancement, efficacy, and safety assessment of azelaic acid loaded SNEDDS hydrogel to overcome the treatment barriers of atopic dermatitis

N Parveen, A Sheikh, N Molugulu, S Annadurai… - Environmental …, 2023 - Elsevier
Atopic dermatitis is one of the most widespread chronic inflammatory skin conditions that
can occur at any age, though the prevalence is highest in children. The purpose of the …

Development of a novel colloidal system enhancing the dispersibility of tocopherol nanoparticles in a nanoscale nutraceutical delivery system

S Yakoubi, I Kobayashi, K Uemura… - Colloids and Surfaces A …, 2023 - Elsevier
The aim of this study is to develop a new binary emulsifier system to be used as a surface-
active agent in a nanometric delivery system. The effect of the interaction between gum …

[HTML][HTML] Regulatory status quo and prospects for biosurfactants in pharmaceutical applications

R Ismail, Z Baaity, I Csóka - Drug Discovery Today, 2021 - Elsevier
The concept of going 'green'and 'cold'has led to utilizing renewable resources for the
synthesis of microbial biosurfactants that are both patient and eco-friendly. In this review, we …

Expanding opportunities to engineer mucosal vaccination with biomaterials

HF Haddad, EF Roe, JH Collier - Biomaterials Science, 2023 - pubs.rsc.org
Mucosal vaccines are receiving increasing interest both for protecting against infectious
diseases and for inducing therapeutic immune responses to treat non-infectious diseases …