Electrospun fibrous meshes are widely used for tissue repair due to their ability to guide a
host of cell responses including phenotypic differentiation and tissue maturation. A critical …

Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …

The formation of a fluid-filled cystic cavity after spinal cord injury (SCI) is a major obstacle for
neural regeneration. In this study, the post-SCI cavity was bridged by a functional self …

Severe liver disease is one of the most common causes of death globally. Currently, whole
organ transplantation is the only therapeutic method for end-stage liver disease treatment …

Three aligned, electrospun fiber scaffolds with unique surface features were created from
poly-L-lactic acid (PLLA). Fibers without surface nanotopography (smooth fibers), fibers with …

Electrospun poly-l-lactic acid (PLLA) fibers are commonly used for tissue engineering
applications because of their uniform morphology, and their efficacy can be further …

Aligned, electrospun fiber scaffolds provide topographical guidance for regenerating
neurons and glia after central nervous system injury. To date, no study has explored how …

Electrospinning is a robust material fabrication method allowing for fine control of
mechanical, chemical, and functional properties in scaffold manufacturing. Electrospun fiber …

Despite the existence of many attempts at nerve tissue engineering, there is no ideal
strategy to date for effectively treating defective peripheral nerve tissue. In the present study …

Biopolymer grafts often have limited biocompatibility, triggering excessive inflammatory
responses similar to foreign bodies. Macrophage phenotype shifts are pivotal in the …