Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Metabolic syndrome is associated with abdominal obesity, blood lipid disorders,
inflammation, insulin resistance or full-blown diabetes, and increased risk of developing …

The prevalence of obesity in the United States and the world has risen to
epidemic/pandemic proportions. This increase has occurred despite great efforts by …

Obesity is a condition likely associated with several dysmetabolic conditions or worsening of
cardiovascular and other chronic disturbances. A key role in this mechanism seem to be …

Although excess visceral fat is associated with noninfectious inflammation, it is not clear
whether visceral fat is simply associated with or actually causes metabolic disease in …

Excess caloric intake can lead to insulin resistance. The underlying reasons are complex but
likely related to ectopic lipid deposition in nonadipose tissue. We hypothesized that the …

Background Rimonabant, a selective cannabinoid-1 receptor (CB1) blocker, has been
shown to reduce body weight and improve cardiovascular risk factors in obese patients. The …

New therapeutic and preventative strategies are needed to address the growing obesity
epidemic. In animal models, brown adipose tissue activation and the associated heat …

Adipose tissue is a complex endocrine organ with an intricate role in whole body
homeostasis. Beyond storing energy, adipose tissue is fundamental in numerous processes …

Despite the fact that controversy remains around the underlying pathophysiological
processes leading to the development of the metabolic syndrome (insulin resistance and/or …