Diversity and dynamism of IgA− microbiota interactions

KE Huus, C Petersen, BB Finlay - Nature Reviews Immunology, 2021 - nature.com
IgA mediates microbial homeostasis at the intestinal mucosa. Within the gut, IgA acts in a
context-dependent manner to both prevent and promote bacterial colonization and to …

Current status of malnutrition and stunting in Pakistani children: what needs to be done?

A Ali - Journal of the American College of Nutrition, 2021 - Taylor & Francis
Malnutrition is one of the greatest health challenges that affects about 2 billion people
globally. Multiple factors including poverty, food insecurity, maternal health and nutritional …

[HTML][HTML] Histopathology underlying environmental enteric dysfunction in a cohort study of undernourished children in Bangladesh, Pakistan, and Zambia compared …

P Kelly, K VanBuskirk, D Coomes, S Mouksassi… - The American Journal of …, 2024 - Elsevier
Background Environmental enteric dysfunction (EED) is an asymptomatic intestinal disorder
associated with growth impairment, delayed neurocognitive development, and impaired oral …

[HTML][HTML] Mucosal genomics implicate lymphocyte activation and lipid metabolism in refractory environmental enteric dysfunction

Y Haberman, NT Iqbal, S Ghandikota… - Gastroenterology, 2021 - Elsevier
Background & Aims Environmental enteric dysfunction (EED) limits the Sustainable
Development Goals of improved childhood growth and survival. We applied mucosal …

NAD+ precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction

A Malique, S Sun, K Chandwe, B Amadi… - Science translational …, 2024 - science.org
Environmental enteric dysfunction (EED) is a diffuse small bowel disorder associated with
poor growth, inadequate responses to oral vaccines, and nutrient malabsorption in millions …

A novel histological index for evaluation of environmental enteric dysfunction identifies geographic-specific features of enteropathy among children with suboptimal …

TC Liu, K VanBuskirk, SA Ali, MP Kelly… - PLoS neglected …, 2020 - journals.plos.org
Background A major limitation to understanding the etiopathogenesis of environmental
enteric dysfunction (EED) is the lack of a comprehensive, reproducible histologic framework …

Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural …

A Sarfraz, S Ahmed, S Muhammad, N Rehman… - Plos one, 2023 - journals.plos.org
Background The reduction in severe and moderate acute malnutrition (SAM and MAM) rates
in Pakistan has been sub-optimal compared to other low-and middle-income countries …

Assessment of machine learning detection of environmental enteropathy and celiac disease in children

S Syed, M Al-Boni, MN Khan, K Sadiq… - JAMA network …, 2019 - jamanetwork.com
Importance Duodenal biopsies from children with enteropathies associated with
undernutrition, such as environmental enteropathy (EE) and celiac disease (CD), display …

[HTML][HTML] Intestinal epithelial digestive, transport, and barrier protein expression is increased in environmental enteric dysfunction

S Abtahi, A Sailer, JT Roland, X Haest… - Laboratory …, 2023 - Elsevier
Environmental enteric dysfunction (EED) is characterized by malabsorption and diarrhea
that result in irreversible deficits in physical and intellectual growth. We sought to define the …

Intestinal biopsies for the evaluation of environmental enteropathy and environmental enteric dysfunction

P Hodges, M Tembo, P Kelly - The Journal of Infectious …, 2021 - academic.oup.com
Environmental enteric dysfunction (EED) is a syndrome characterized by impairments of
digestion and absorption and intestinal barrier failure in people living in insanitary or tropical …