Paclitaxel is a natural anticancer compound with minimal toxicity, the capacity to stabilize
microtubules, and high efficiency that has remained the standard of treatment alongside …

Flavonoids are present in fruits, vegetables and beverages derived from plants (tea, red
wine), and in many dietary supplements or herbal remedies including Ginkgo Biloba, Soy …

Chemotherapy forms the mainstay of cancer treatment particularly for patients who do not
respond to local excision or radiation treatment. However, cancer treatment by drugs is …

The present article aims to review the up-to-date information on the most recent studies of
the interaction of flavonoids with ABC transporters, in particular the drug pharmacokinetic …

Multidrug resistance caused by the overexpression of ABC drug transporters is a major
obstacle in clinical cancer chemotherapy. For several years, it appeared that direct inhibition …

d-alpha-tocopheryl poly (ethylene glycol) 1000 succinate (TPGS 1000) is a widely used form
of vitamin E. TPGS 1000 is comprised of a hydrophilic polar (water-soluble) head and a …

The transcellular transport of ingested food ingredients across the intestinal epithelial barrier
is an important factor determining bioavailability upon oral intake. This transcellular transport …

In recent years, public and scientific interest in plant flavonoids has tremendously increased
due to postulated health benefits. Whereas the amount of flavonoids ingested with the …

ATP-binding cassette (ABC) transporters are transmembrane efflux transporters that mediate
cellular extrusion of a broad range of substrates ranging from amino acids, lipids, and ions to …

A trend in the general population has been observed in recent years regarding the
orientation toward preventive measures in health; in this context the increased interest from …