Innovative tools and approaches to end the transmission of Mycobacterium leprae

P Steinmann, SG Reed, F Mirza… - The Lancet Infectious …, 2017 - thelancet.com
Leprosy control has seen little innovation and only limited progress in the past decade.
However, research on the disease has increased and important innovations are underway …

[PDF][PDF] Prevention of transmission of leprosy: the current scenario

A Palit, HK Kar - Indian journal of dermatology, venereology and …, 2020 - ijdvl.com
With the worldwide implementation of WHO multidrug therapy in the 1980s, the global
burden of leprosy has decreased. However, the annual new case detection rate around the …

Global elimination of leprosy by 2020: are we on track?

DJ Blok, SJ De Vlas, JH Richardus - Parasites & vectors, 2015 - Springer
Background Every year more than 200,000 new leprosy cases are registered globally. This
number has been fairly stable over the past 8 years. WHO has set a target to interrupt the …

Number of people requiring post-exposure prophylaxis to end leprosy: A modeling study

AT Taal, DJ Blok, WH van Brakel… - PLoS neglected …, 2021 - journals.plos.org
Background Worldwide, around 210,000 new cases of leprosy are detected annually. To
end leprosy, ie zero new leprosy cases, preventive interventions such as contact tracing and …

A comprehensive research agenda for zero leprosy

P Steinmann, C Dusenbury, D Addiss, F Mirza… - Infectious diseases of …, 2020 - Springer
Background Leprosy control achieved dramatic success in the 1980s–1990s with the
implementation of short course multidrug therapy, which reduced the global prevalence of …

Vaccines for leprosy and tuberculosis: opportunities for shared research, development, and application

M Coppola, SJF van den Eeden, N Robbins… - Frontiers in …, 2018 - frontiersin.org
Tuberculosis (TB) and leprosy still represent significant public health challenges, especially
in low-and lower middle-income countries. Both poverty-related mycobacterial diseases …

Leprosy new case detection trends and the future effect of preventive interventions in Pará State, Brazil: a modelling study

HJ de Matos, DJ Blok, SJ de Vlas… - PLoS neglected tropical …, 2016 - journals.plos.org
Background Leprosy remains a public health problem in Brazil. Although the overall number
of new cases is declining, there are still areas with a high disease burden, such as Pará …

Mathematical modeling and control of the cell dynamics in leprosy

S Ghosh, AN Chatterjee, PK Roy, N Grigorenko… - Computational …, 2021 - Springer
Leprosy (Hansen's disease) is an infectious, neglected tropical disease caused by the
bacterium or scientifically Mycobacterium Leprae (M. Leprae). Every year approximately …

Leprosy post-exposure prophylaxis in the Indian health system: A cost-effectiveness analysis

A Tiwari, DJ Blok, M Arif… - PLoS Neglected Tropical …, 2020 - journals.plos.org
India has the highest burden of leprosy in the world. Following a recent WHO guideline, the
Indian National Leprosy Programme is introducing post-exposure prophylaxis with single …

The long-term impact of the leprosy post-exposure prophylaxis (LPEP) program on leprosy incidence: a modelling study

DJ Blok, P Steinmann, A Tiwari… - PLOS Neglected …, 2021 - journals.plos.org
Background The Leprosy Post-Exposure Prophylaxis (LPEP) program explored the
feasibility and impact of contact tracing and the provision of single dose rifampicin (SDR) to …