Oxidative stress and natural antioxidants in osteoporosis: Novel preventive and therapeutic approaches
G Marcucci, V Domazetovic, C Nediani, J Ruzzolini… - Antioxidants, 2023 - mdpi.com
This review reports in detail the cellular and molecular mechanisms which regulate the bone
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …
Modulation of redox-sensitive transcription factors with polyphenols as pathogenetically grounded approach in therapy of systemic inflammatory response
One of the adverse outcomes of acute inflammatory response is progressing to the chronic
stage or transforming into an aggressive process, which can develop rapidly and result in …
stage or transforming into an aggressive process, which can develop rapidly and result in …
Ferroptosis-a new target of osteoporosis
Z Gao, Z Chen, Z Xiong, X Liu - Experimental gerontology, 2022 - Elsevier
Osteoporosis is a bone metabolic disease characterized by reduced bone mass and
deterioration of bone tissue microarchitecture, leading to enhanced skeletal fragility and …
deterioration of bone tissue microarchitecture, leading to enhanced skeletal fragility and …
ROS-activatable biomimetic interface mediates in-situ bioenergetic remodeling of osteogenic cells for osteoporotic bone repair
M Chen, M Li, Y Wei, C Xue, M Chen, Y Fei, L Tan… - Biomaterials, 2022 - Elsevier
Bioenergy (ATP) is essentially required for supporting the osteogenic differentiation of bone
marrow mesenchymal stem cells (MSCs). However, factors such as high ROS levels and …
marrow mesenchymal stem cells (MSCs). However, factors such as high ROS levels and …
Prussian blue nanozyme normalizes microenvironment to delay osteoporosis
C Ye, W Zhang, Y Zhao, K Zhang… - Advanced …, 2022 - Wiley Online Library
Osteoporosis (OP) is the most common orthopedic disease in the elderly and the main
cause of age‐related mortality and disability. However, no satisfactory intervention is …
cause of age‐related mortality and disability. However, no satisfactory intervention is …
The “three in one” bone repair strategy for osteoporotic fractures
X Chen, Y Hu, Z Geng, J Su - Frontiers in endocrinology, 2022 - frontiersin.org
In aging society, osteoporotic fractures have become one major social problem threatening
the health of the elderly population in China. Compared with conventional fractures, low …
the health of the elderly population in China. Compared with conventional fractures, low …
[HTML][HTML] The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies
Y Zhang, J Liang, P Liu, Q Wang, L Liu… - Frontiers in …, 2022 - frontiersin.org
With the markedly increased diagnosis and incidence of cancer in the population, tumor
bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is …
bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is …
A Glutathione Peroxidase‐Mimicking Nanozyme Precisely Alleviates Reactive Oxygen Species and Promotes Periodontal Bone Regeneration
B Zhu, J Wu, T Li, S Liu, J Guo, Y Yu… - Advanced …, 2024 - Wiley Online Library
The use of oxidoreductase nanozymes to regulate reactive oxygen species (ROS) has
gradually emerged in periodontology treatments. However, current nanozymes for treating …
gradually emerged in periodontology treatments. However, current nanozymes for treating …
Research progress of ferroptosis regulatory network and bone remodeling in osteoporosis
C Yan, J Zhang, F An, J Wang, Y Shi, L Yuan… - Frontiers in Public …, 2022 - frontiersin.org
Ferroptosis was induced the programmed cell death with iron overload Fenton reaction.
Currently, ferroptosis has not been studied thoroughly. Existing studies have confirmed that …
Currently, ferroptosis has not been studied thoroughly. Existing studies have confirmed that …
Citropten Ameliorates Osteoclastogenesis Related to MAPK and PLCγ/Ca2+ Signaling Pathways through the Regulation of Amyloid Beta
Osteoporosis and Alzheimer's disease are typical types of dementia in seniors, which share
common risk factors. Previous studies have shown that citizens with osteoporosis are more …
common risk factors. Previous studies have shown that citizens with osteoporosis are more …